Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3022333..3022501 Replicon chromosome
Accession NZ_CP067093
Organism Klebsiella michiganensis strain B106

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3022391..3022494 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3022333..3022501 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMZ21_RS14230 3017459..3019519 + 2061 WP_032741886.1 oligopeptidase B -
IMZ21_RS14235 3019526..3020185 - 660 WP_004122030.1 exodeoxyribonuclease X -
IMZ21_RS14240 3020264..3020494 - 231 WP_004122029.1 DNA polymerase III subunit theta -
IMZ21_RS14245 3020630..3021004 + 375 WP_123829166.1 CopC domain-containing protein YobA -
IMZ21_RS14250 3021009..3021878 + 870 WP_087828997.1 copper homeostasis membrane protein CopD -
IMZ21_RS14255 3021895..3022233 + 339 WP_004122026.1 YebY family protein -
- 3022333..3022501 - 169 - - Antitoxin
- 3022391..3022494 + 104 - - Toxin
IMZ21_RS14260 3022619..3023578 - 960 WP_123829167.1 spore coat U domain-containing protein -
IMZ21_RS14265 3023593..3025923 - 2331 WP_200482946.1 fimbria/pilus outer membrane usher protein -
IMZ21_RS14270 3025926..3026690 - 765 WP_123829169.1 molecular chaperone -
IMZ21_RS14275 3026709..3027227 - 519 WP_004122022.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T185738 NZ_CP067093:3022391-3022494 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT185738 NZ_CP067093:c3022501-3022333 [Klebsiella michiganensis]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References