Detailed information of TA system TA185705

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-RelB
• Location: 2219730..2220346
• Replicon: chromosome
• Accession: NZ_CP067087
• Organism: Croceicoccus sp. YJ47

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JD971_RS10860
• Protein ID: WP_202083339.1
• Coordinates: 2219730..2220056 (-)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JD971_RS10865
• Protein ID: WP_202083342.1
• Coordinates: 2220053..2220346 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JD971_RS10850	2216484..2217677	-	1194	WP_202083335.1	GIY-YIG nuclease family protein	-
JD971_RS10855	2217670..2219733	-	2064	WP_202083337.1	DEAD/DEAH box helicase	-
JD971_RS10860	2219730..2220056	-	327	WP_202083339.1	type II toxin-antitoxin system YafQ family toxin	Toxin
JD971_RS10865	2220053..2220346	-	294	WP_202083342.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
JD971_RS10870	2220463..2221044	-	582	WP_202083344.1	hypothetical protein	-
JD971_RS10875	2221081..2223828	-	2748	WP_202087577.1	N-6 DNA methylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2208234..2225414	17180

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (14-108)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-62)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12174.15 Da
• Isoelectric Point: 10.3736

>T185705 WP_202083339.1 NZ_CP067087:c2220056-2219730 [Croceicoccus sp. YJ47]
MKKAAASKRAALPRTIGYAKSFLKDFERLSRSGRYDMKKLKQVMLLLIANDAPLGPEWKDHTLKGEWQGHRECHVGGDFL
LIYRVDDIPAPGGGIFFTRAGTHSELFK

Nucleotide

• Length: 327 bp

>T185705 NZ_CP089000:c110942-110631 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10755.10 Da
• Isoelectric Point: 4.5129

>AT185705 WP_202083342.1 NZ_CP067087:c2220346-2220053 [Croceicoccus sp. YJ47]
MIHVRMDNDLKDRATEALAAMGLSTADAVRLLFHRIATDQAFPLELKVPNAETRAAMEEADEFFKNGGAPRFDNADEMFA
ELEEESKALREAGKAKS

Nucleotide

• Length: 294 bp

>AT185705 NZ_CP089000:c110634-110215 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA