Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3991092..3991735 Replicon chromosome
Accession NZ_CP067071
Organism Rhizobium sp. AB2/73

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I8E17_RS19630 Protein ID WP_113366582.1
Coordinates 3991092..3991496 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I8E17_RS19635 Protein ID WP_113366583.1
Coordinates 3991493..3991735 (-) Length 81 a.a.

Genomic Context

I8E17_RS19595I8E17_RS19605I8E17_RS19610I8E17_RS19615I8E17_RS19620I8E17_RS19625I8E17_RS19600I8E17_RS19630I8E17_RS19635I8E17_RS19640I8E17_RS19645I8E17_RS19650I8E17_RS19655
Location: 3986171..3987082 (912 bp)
Type: Others
Protein ID: WP_113366577.1
Location: 3988102..3989385 (1284 bp)
Type: Others
Protein ID: WP_113366578.1
Location: 3989400..3989786 (387 bp)
Type: Others
Protein ID: WP_069611110.1
Location: 3989878..3990219 (342 bp)
Type: Others
Protein ID: WP_113366579.1
Location: 3990203..3990685 (483 bp)
Type: Others
Protein ID: WP_113366580.1
Location: 3990691..3991095 (405 bp)
Type: Others
Protein ID: WP_113366581.1
Location: 3987128..3988003 (876 bp)
Type: Others
Protein ID: WP_069611108.1
Location: 3991092..3991496 (405 bp)
Type: Toxin
Protein ID: WP_113366582.1
Location: 3991493..3991735 (243 bp)
Type: Antitoxin
Protein ID: WP_113366583.1
Location: 3991801..3992475 (675 bp)
Type: Others
Protein ID: WP_113366584.1
Location: 3992545..3994206 (1662 bp)
Type: Others
Protein ID: WP_113366585.1
Location: 3994249..3994578 (330 bp)
Type: Others
Protein ID: WP_069611116.1
Location: 3994597..3995697 (1101 bp)
Type: Others
Protein ID: WP_069611117.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I8E17_RS19595 (I8E17_19580)3986171..3987082+912WP_113366577.1LysR family transcriptional regulator-
I8E17_RS19600 (I8E17_19585)3987128..3988003-876WP_069611108.1LysR family transcriptional regulator-
I8E17_RS19605 (I8E17_19590)3988102..3989385+1284WP_113366578.1MFS transporter-
I8E17_RS19610 (I8E17_19595)3989400..3989786+387WP_069611110.1VOC family protein-
I8E17_RS19615 (I8E17_19600)3989878..3990219+342WP_113366579.1metalloregulator ArsR/SmtB family transcription factor-
I8E17_RS19620 (I8E17_19605)3990203..3990685+483WP_113366580.1SRPBCC domain-containing protein-
I8E17_RS19625 (I8E17_19610)3990691..3991095+405WP_113366581.1GFA family protein-
I8E17_RS19630 (I8E17_19615)3991092..3991496-405WP_113366582.1type II toxin-antitoxin system VapC family toxinToxin
I8E17_RS19635 (I8E17_19620)3991493..3991735-243WP_113366583.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
I8E17_RS19640 (I8E17_19625)3991801..3992475-675WP_113366584.1hypothetical protein-
I8E17_RS19645 (I8E17_19630)3992545..3994206-1662WP_113366585.1urocanate hydratase-
I8E17_RS19650 (I8E17_19635)3994249..3994578-330WP_069611116.1TfoX/Sxy family protein-
I8E17_RS19655 (I8E17_19640)3994597..3995697-1101WP_069611117.1DUF917 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14753.00 Da        Isoelectric Point: 8.4869

>T185699 WP_113366582.1 NZ_CP067071:c3991496-3991092 [Rhizobium sp. AB2/73]
VKYLLDSNAIIALMKGHPGFVGKLRRHKPQDFAIPAIVAHELIYGAYKGQRVSDNLARVDALQFETLDFDKQDARVAGEI
RASLASLGTPIGAYDVLIAGQAVARDLILITHNVKEFGRVPKLRFEDWESLPSG

Download         Length: 405 bp

>T185699 NZ_CP088997:c4776623-4776090 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9285.42 Da        Isoelectric Point: 4.2296

>AT185699 WP_113366583.1 NZ_CP067071:c3991735-3991493 [Rhizobium sp. AB2/73]
MDTAKIFWSGRSQAVRLPKEFRLDGEEVRIRRQGKAIILEPITEDWDWLEAVTGPVDDDFVEAATEQPAEQQRPELDIFK

Download         Length: 243 bp

>AT185699 NZ_CP088997:c4776900-4776634 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References