Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-parD/RelE-RHH |
| Location | 3694045..3694628 | Replicon | chromosome |
| Accession | NZ_CP067071 | ||
| Organism | Rhizobium sp. AB2/73 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | I8E17_RS18105 | Protein ID | WP_113366807.1 |
| Coordinates | 3694045..3694341 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | - |
| Locus tag | I8E17_RS18110 | Protein ID | WP_113366806.1 |
| Coordinates | 3694338..3694628 (-) | Length | 97 a.a. |
Genomic Context
Location: 3693303..3694037 (735 bp)
Type: Others
Protein ID: WP_113366808.1
Type: Others
Protein ID: WP_113366808.1
Location: 3689305..3690081 (777 bp)
Type: Others
Protein ID: WP_113366811.1
Type: Others
Protein ID: WP_113366811.1
Location: 3690078..3690989 (912 bp)
Type: Others
Protein ID: WP_069610920.1
Type: Others
Protein ID: WP_069610920.1
Location: 3690986..3692095 (1110 bp)
Type: Others
Protein ID: WP_113366810.1
Type: Others
Protein ID: WP_113366810.1
Location: 3692099..3692725 (627 bp)
Type: Others
Protein ID: WP_113366809.1
Type: Others
Protein ID: WP_113366809.1
Location: 3692725..3693201 (477 bp)
Type: Others
Protein ID: WP_112722845.1
Type: Others
Protein ID: WP_112722845.1
Location: 3694045..3694341 (297 bp)
Type: Toxin
Protein ID: WP_113366807.1
Type: Toxin
Protein ID: WP_113366807.1
Location: 3694338..3694628 (291 bp)
Type: Antitoxin
Protein ID: WP_113366806.1
Type: Antitoxin
Protein ID: WP_113366806.1
Location: 3694728..3695363 (636 bp)
Type: Others
Protein ID: WP_112722848.1
Type: Others
Protein ID: WP_112722848.1
Location: 3695485..3696309 (825 bp)
Type: Others
Protein ID: WP_113366805.1
Type: Others
Protein ID: WP_113366805.1
Location: 3696324..3698117 (1794 bp)
Type: Others
Protein ID: WP_112722850.1
Type: Others
Protein ID: WP_112722850.1
Location: 3698329..3699351 (1023 bp)
Type: Others
Protein ID: WP_112722851.1
Type: Others
Protein ID: WP_112722851.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I8E17_RS18075 (I8E17_18065) | 3689305..3690081 | - | 777 | WP_113366811.1 | phosphonate C-P lyase system protein PhnK | - |
| I8E17_RS18080 (I8E17_18070) | 3690078..3690989 | - | 912 | WP_069610920.1 | alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ | - |
| I8E17_RS18085 (I8E17_18075) | 3690986..3692095 | - | 1110 | WP_113366810.1 | carbon-phosphorus lyase complex subunit PhnI | - |
| I8E17_RS18090 (I8E17_18080) | 3692099..3692725 | - | 627 | WP_113366809.1 | phosphonate C-P lyase system protein PhnH | - |
| I8E17_RS18095 (I8E17_18085) | 3692725..3693201 | - | 477 | WP_112722845.1 | phosphonate C-P lyase system protein PhnG | - |
| I8E17_RS18100 (I8E17_18090) | 3693303..3694037 | + | 735 | WP_113366808.1 | phosphonate metabolism transcriptional regulator PhnF | - |
| I8E17_RS18105 (I8E17_18095) | 3694045..3694341 | - | 297 | WP_113366807.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| I8E17_RS18110 (I8E17_18100) | 3694338..3694628 | - | 291 | WP_113366806.1 | hypothetical protein | Antitoxin |
| I8E17_RS18115 (I8E17_18105) | 3694728..3695363 | - | 636 | WP_112722848.1 | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | - |
| I8E17_RS18120 (I8E17_18110) | 3695485..3696309 | - | 825 | WP_113366805.1 | 4-hydroxy-tetrahydrodipicolinate reductase | - |
| I8E17_RS18125 (I8E17_18115) | 3696324..3698117 | - | 1794 | WP_112722850.1 | ABC transporter ATP-binding protein | - |
| I8E17_RS18130 (I8E17_18120) | 3698329..3699351 | - | 1023 | WP_112722851.1 | glucokinase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11175.92 Da Isoelectric Point: 9.5301
>T185698 WP_113366807.1 NZ_CP067071:c3694341-3694045 [Rhizobium sp. AB2/73]
VKLAWTPEARADRRAIYTYIEAENATAALALDELLAKRSKQLITHPMTGRPGRVSGTRELVVHRNYLLVYDLADEMVRII
RILHAAQQWPPSDFQPIP
VKLAWTPEARADRRAIYTYIEAENATAALALDELLAKRSKQLITHPMTGRPGRVSGTRELVVHRNYLLVYDLADEMVRII
RILHAAQQWPPSDFQPIP
Download Length: 297 bp
>T185698 NZ_CP088997:4163801-4164019 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10872.98 Da Isoelectric Point: 4.6812
>AT185698 WP_113366806.1 NZ_CP067071:c3694628-3694338 [Rhizobium sp. AB2/73]
MTDATFTFRVEEELKAAFSEAAKAHDQTGAQLLRAFMRDYVRRQQDAAEYDIWFRQQVQAGLTSANAGNLIPDDDVDAEF
AALREETRRKLSGRSS
MTDATFTFRVEEELKAAFSEAAKAHDQTGAQLLRAFMRDYVRRQQDAAEYDIWFRQQVQAGLTSANAGNLIPDDDVDAEF
AALREETRRKLSGRSS
Download Length: 291 bp
>AT185698 NZ_CP088997:4163400-4163774 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG