Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2031917..2032062 Replicon chromosome
Accession NZ_CP067060
Organism Klebsiella pneumoniae strain ZJ27003

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2031953..2032055 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2031917..2032062 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JE026_RS09650 2027047..2029107 + 2061 WP_004151449.1 oligopeptidase B -
JE026_RS09655 2029111..2029770 - 660 WP_002911407.1 exodeoxyribonuclease X -
JE026_RS09660 2029849..2030079 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JE026_RS09665 2030192..2030566 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JE026_RS09670 2030570..2031439 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
JE026_RS09675 2031456..2031794 + 339 WP_002911404.1 YebY family protein -
- 2031917..2032062 - 146 - - Antitoxin
- 2031953..2032055 + 103 - - Toxin
JE026_RS09680 2032430..2032573 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JE026_RS09685 2032678..2033646 - 969 WP_014907334.1 VirK/YbjX family protein -
JE026_RS09690 2033803..2034456 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JE026_RS09695 2034453..2034644 - 192 WP_002911395.1 YebW family protein -
JE026_RS09700 2034742..2034981 - 240 WP_002911393.1 YebV family protein -
JE026_RS09705 2035097..2036530 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185657 NZ_CP067060:2031953-2032055 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185657 NZ_CP067060:c2032062-2031917 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References