Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3882156..3882669 Replicon chromosome
Accession NZ_CP067024
Organism Pseudomonas syringae pv. maculicola strain MAFF 302723

Toxin (Protein)


Gene name relE Uniprot ID Q87YW5
Locus tag JHZ65_RS17305 Protein ID WP_011104666.1
Coordinates 3882385..3882669 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UR83
Locus tag JHZ65_RS17300 Protein ID WP_005740683.1
Coordinates 3882156..3882395 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JHZ65_RS17280 3878331..3879116 + 786 WP_005765329.1 membrane protein -
JHZ65_RS17285 3879243..3880151 - 909 WP_054089894.1 DUF808 domain-containing protein -
JHZ65_RS17290 3880299..3880805 - 507 WP_054080259.1 winged helix-turn-helix transcriptional regulator -
JHZ65_RS17295 3880971..3881987 + 1017 WP_003376162.1 1-aminocyclopropane-1-carboxylate deaminase -
JHZ65_RS17300 3882156..3882395 + 240 WP_005740683.1 ribbon-helix-helix protein, CopG family Antitoxin
JHZ65_RS17305 3882385..3882669 + 285 WP_011104666.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JHZ65_RS17310 3882705..3883559 - 855 WP_011104667.1 LysR family transcriptional regulator -
JHZ65_RS17315 3883634..3884566 + 933 WP_122388836.1 DMT family transporter -
JHZ65_RS17320 3884595..3886523 - 1929 WP_044390209.1 methyl-accepting chemotaxis protein -
JHZ65_RS17325 3886775..3887260 - 486 WP_007245243.1 DUF2269 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-40)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10838.62 Da        Isoelectric Point: 10.0884

>T185590 WP_011104666.1 NZ_CP067024:3882385-3882669 [Pseudomonas syringae pv. maculicola]
MQVEWLKTALKNLDDEAAYISLENPAAAVAFVEALQISVKQLASFPALGREGRIAGTREWPLPDWPYLIPYRIRNGRLQV
LRIFHTRRQPPLVW

Download         Length: 285 bp

>T185590 NZ_CP088923:3696343-3696537 [Rhodanobacter thiooxydans]
ATGTCGAACTTCGTCGCGATGTTCGACGCCTGCGTGTTGTACCGCGAATCCCTGCGCAATCTCTTGCTACATCTCGCCCT
GAGTGGCTTGTACCGCGCGCGCTGGACTGCGCGCGTACACGAAGAATGGATCAGGGCATTGTGCGCCAGCGTCCCGATCT
TTCCCGCGACGATCTGGAGCGAACTCGACGACTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8753.90 Da        Isoelectric Point: 4.5822

>AT185590 WP_005740683.1 NZ_CP067024:3882156-3882395 [Pseudomonas syringae pv. maculicola]
MSVMSLRLPDEMADTLAHLAKATGRSKSFLALNALREYLTREAWQIAEIQRAIEEADAGEFASEEDVKAVMNKWANNAG

Download         Length: 240 bp

>AT185590 NZ_CP088923:3695881-3696339 [Rhodanobacter thiooxydans]
ATGACCGCCCTGCGCAACGAACAACTCGTCAACCTGCCCGCCACTCCCCAGGAATCCGAACTGGCGCGCACCAGCAGCCG
CCTGCTGGCGGCCTGTATCGGCCACGGCTCCACCGCACGCCTGCGCGTGATCGACGGCGAGCAGGAGATCGAGGTGCCGG
TGGCGGCACTGCGAATGCTGGTAGACATCCTCGCCAACATGGCCGAAGGCAACGCGATGAGCCTGGTCCCGGTCCATGCC
GAGCTCACCACGCAGCAAGCCGCGGATTTTCTCAACGTCTCACGGCCGTACCTGGTCGGCTTGATCGATCGCGGCGAGCT
GACCCATCACAAGGTCGGCACGCATCGACGTATCTATTTCCGCGACCTGATGGCGTACCGCGAGCAACGTCTGATGCAGA
GCCATGCAGCACTGGACGCCCTAGCCGAACAGGCACAAAAACTCGATCTGGACTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q87YW5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M7Q4

References