185587

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 1722543..1722988 Replicon chromosome
Accession NZ_CP067022
Organism Pseudomonas cannabina pv. alisalensis strain MAFF 301419

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag JGS08_RS07875 Protein ID WP_122320264.1
Coordinates 1722543..1722671 (+) Length 43 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID A0A0K8LSV9
Locus tag JGS08_RS07880 Protein ID WP_004397562.1
Coordinates 1722668..1722988 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGS08_RS07850 1718298..1719005 - 708 WP_054080063.1 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO -
JGS08_RS07855 1719019..1719480 - 462 WP_007250188.1 DUF1456 family protein -
JGS08_RS07860 1719557..1720267 - 711 WP_007250189.1 rRNA pseudouridine synthase -
JGS08_RS07865 1720361..1720801 - 441 WP_007250190.1 GNAT family N-acetyltransferase -
JGS08_RS07870 1720918..1722261 - 1344 WP_007250191.1 30S ribosomal protein S12 methylthiotransferase RimO -
JGS08_RS07875 1722543..1722671 + 129 WP_122320264.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JGS08_RS07880 1722668..1722988 + 321 WP_004397562.1 helix-turn-helix domain-containing protein Antitoxin
JGS08_RS07885 1723083..1724174 - 1092 WP_007250193.1 catalase family protein -
JGS08_RS07890 1724480..1726375 + 1896 WP_054080062.1 potassium transporter Kup -
JGS08_RS07895 1726468..1727802 - 1335 WP_007250195.1 virulence factor family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(2-31)

Antitoxin

HigA2-like, helix-turn-helix domain

(11-90)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4795.60 Da        Isoelectric Point: 10.8288

>T185587 WP_122320264.1 NZ_CP067022:1722543-1722671 [Pseudomonas cannabina pv. alisalensis]
MVYVLHCFQKKSTSGIKTAKHDIELIKSRLKAAQAHAESNRR

Download         Length: 129 bp

>T185587 NZ_CP088923:1392773-1393636 [Rhodanobacter thiooxydans]
ATGAGCCGAAACGTGGCCGCCTCGGTACGTGCCCGGCTGAAAAACCGGGCCGACGCCACGCAAGAGGATTACAACCTGCT
GCTGACGCGCTACGGACTGGAGCGGCTGCTGTACCGATTGTCGGTGTCGCCGCACGCGCCGAATTTTCTGCTCAAGGGGG
CGTTGCTGTTCCTGCTGTGGCATGAGCTGCCGCATCGGCCTACCCGTGACGCAGACCTGCTCGGCTTTGGCGACGCCGAT
GTCGATCCGGTGGTGGCCGTATTCCGTCAGGTCTGCGCGGTGGCCTGCGATGACGGCATGCGCTTCGATACCCGCTCGAT
TCGTGGCGAGGTGATCCGCAAGCAGGCCGGTTACAGCGGGGTGCGGATCGAGATACAGGCCACGCTGGATGCTGCCGTGC
TGAGCCTGCAGGTCGATGTCGGCTTTGGCGATGTGGTGACGCCGGCCGCATTGGCGGTGACATACCCGGTGCTGCTGGAT
GACTTGCCTGCACCGCAGCTGCGTGCCTACCCGAAGTACACGGTGTGTGCCGAGAAGCTGCAGGCACTGTGCGTGCTCGG
CATGGCCAATACGCGCCTGAAGGACTATTTCGACCTGTGGCTGCTGCTGGGCGAGGGCAGTCTGGATACCTCGTTGCTGG
GGCGTGCGATCGCTGCCACGTTCGGGCGCCGCGGCACGGCCTTGCCGGACGGTTGGCCGGCGGGGCTGAGCGACCTCTTT
GCGACCGATGCGGGCAAGCAGCGCCAATGGCAGGCATTTCTGCGAAAGAATCGGCTGGACGCGCCGGACTTGGCCGACGT
GATCAGGGAACTGCGGACTGCGCTGGCGCAACCGTTAGACATGGCAAGGGGACCGTCGGCATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11639.62 Da        Isoelectric Point: 10.2027

>AT185587 WP_004397562.1 NZ_CP067022:1722668-1722988 [Pseudomonas cannabina pv. alisalensis]
MIDIEEGSGNVYADLGRADANEMSIKAQLASKIGTIIKARHLTQLQAAEILAMPQPKVSEMLRGKFRGISEAKMMDCLSR
LGRDVQIVVKAAPRSRREGRVEVVFA

Download         Length: 321 bp

>AT185587 NZ_CP088923:1392134-1392748 [Rhodanobacter thiooxydans]
ATGACCAAGCCTCCGCTCAATCACGAAAAACAGATACTGGCGCTGGCACGCAAGCAGCCTCTGCTGCGCGCGCGCGATCT
GGCGGCACATGGGCTGCCCACGATGACGCTGAGCCGGCTGGTGGCGGCTGGCAAGCTGCAACGGGTGGCGCGCGGGGTAT
ACAGCCTGCCGCAACGCGCGATCAGCGCGCACCGTTCACTGGCCGAGGTGGCAATTCGCGTGCCGCGCGGGGTGGTGTGT
CTGCTGTCGGCGCTGCGCCTGCACGGGATCGGCACCCAGGCACCGTTCGAGGTGTGGCTGGCTATCCCGCAAACCATGCC
GACGCCGCGGCTGAAGCAGCCGGCGCTGAGGGTAGTGCGCATGTCGGGTAGTGCGTTGAGCGAGGGAATCGAGCAGGTCG
ACGTGGATGGTGTCGCCGTGTCGGTGTTCAACCTGGGCAAGACGGTGGCGGACTGCTTCAAGTACCGCAACAAGATCGGT
CTGGATGTGGCGCTGGAGGCGCTGGGTGAGGCCTGGCGCGCGCGCCGGGTAACGATGGACGAGCTGTGGCACTACGCCAC
TATCGACCGCGTGCACAACGTGATGCGGCCGTATCTGGAGGCGCTGGATGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8LSV9

References