Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1057958..1058592 Replicon chromosome
Accession NZ_CP067022
Organism Pseudomonas cannabina pv. alisalensis strain MAFF 301419

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JGS08_RS04755 Protein ID WP_007253051.1
Coordinates 1057958..1058362 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JGS08_RS04760 Protein ID WP_007253050.1
Coordinates 1058362..1058592 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JGS08_RS04730 1053682..1054686 + 1005 WP_054079889.1 response regulator -
JGS08_RS04735 1054690..1055172 + 483 WP_007253055.1 PAS domain-containing protein -
JGS08_RS04740 1055269..1056525 + 1257 WP_007253054.1 3-phosphoshikimate 1-carboxyvinyltransferase -
JGS08_RS04745 1056548..1057210 - 663 WP_007253053.1 ChrR family anti-sigma-E factor -
JGS08_RS04750 1057210..1057722 - 513 WP_042914275.1 sigma-70 family RNA polymerase sigma factor -
JGS08_RS04755 1057958..1058362 - 405 WP_007253051.1 tRNA(fMet)-specific endonuclease VapC Toxin
JGS08_RS04760 1058362..1058592 - 231 WP_007253050.1 antitoxin Antitoxin
JGS08_RS04765 1058883..1059455 + 573 WP_042914268.1 hypothetical protein -
JGS08_RS04770 1059462..1060331 - 870 WP_007253048.1 aldose 1-epimerase -
JGS08_RS04775 1060306..1061277 - 972 WP_007253047.1 DMT family transporter -
JGS08_RS04780 1061357..1062639 - 1283 Protein_933 TRAP transporter large permease -
JGS08_RS04785 1062640..1063167 - 528 WP_054079890.1 TRAP transporter small permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-33)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14968.35 Da        Isoelectric Point: 6.8617

>T185586 WP_007253051.1 NZ_CP067022:c1058362-1057958 [Pseudomonas cannabina pv. alisalensis]
MLKYMLDTNICIFTIKNKPLSVRETFNLHHGQLCISAITLMELVYGAEKSLSPERNLAVVEGFTARLEVLPYDNDAAAHT
GMIRAELARAGTPIGPYDQMIAGHARALGLIIVTNNLREFQRVEGVRVDDWVTR

Download         Length: 405 bp

>T185586 NZ_CP088923:c1007381-1006854 [Rhodanobacter thiooxydans]
ATGAGCGTCCCCGCCTGGCACGAGGAACCGATCTCCAAGAAACATGATCGCAAGTTGTTCGACTGCGGCGATTCCGCGAT
GAACGAGTTCCTTCACAAGTACGCGCGTCAGAGTCACGAGGCCGGCGGCGCGAAAACCTTTGTCGCCGTCGACGACGCGG
ACGGCAAGACGGTTCTCGGCTTTTACAGCTTGGCGCCTGGGGCGCTCGCTTACGCGGATACGCCCGAGCAGGTGCGCAAG
GGCTTGGCGCATCACGACGTGCCGGGTTTTAGGCTCGCGCGCATCGCGACGGACAAACGGCTGCAAGGCGGTGGTCTCGG
CGGTCAGCTCCTCGCGATGGCCGCACGGCGCTGCTTGCGCGCCGCCGACGTTGTGGGGGGGGTCTTGCTCATGATCGATG
CGAAGAACGGGAGCGCAGCCGCGTGGTACGCCAGCTATGGCGCCATGACACTCCCCGACAAGCCGCTCACGCTGGTGATG
GCCCTCGCGACGTTCGAGGCGGAACTGAAGGCGAAAGATCTTCTGTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8595.58 Da        Isoelectric Point: 4.7247

>AT185586 WP_007253050.1 NZ_CP067022:c1058592-1058362 [Pseudomonas cannabina pv. alisalensis]
MEQSTVFKSNRSQAVRLPKAVALPDDVKRVDVVAVGRTRIISPAGESWNIWFEGENVSDDFMTAREQPADQQRESF

Download         Length: 231 bp

>AT185586 NZ_CP088923:c1007656-1007378 [Rhodanobacter thiooxydans]
ATGCCCCGAGTCGCTGTCGATGACAACAAGCGGATGAATCTGCGGGTCTTGCCCGAACAGAAGGCCACGCTCGTGCGGGC
GGCCGCGCTGCGGCACACGGATCTGACAGATTTCGTGCTGCAACCAGCCTTGCGCGAAGCCAAGGCGGTGATCGCGGAGG
CCGAGCGCATCGTCCTGTCGGAAAGGGACAGTGTTGCGGTGCTGAGGATGCTCGAAAACCCGCCGGCGCCGAACGCCAAG
CTGCGCAAGGCTATCGCAGCGCTGCCCAAGCAGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References