Detailed information of TA system TA185582

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PsyrTA/-
• Location: 2410839..2413051
• Replicon: chromosome
• Accession: NZ_CP067019
• Organism: Acinetobacter sp. CS-2

Toxin (Protein)

• Gene name: PsyrT
• Uniprot ID: -
• Locus tag: JFY49_RS11845
• Protein ID: WP_200223053.1
• Coordinates: 2410839..2411771 (+)
• Length: 311 a.a.

Antitoxin (Protein)

• Gene name: PsyrA
• Uniprot ID: -
• Locus tag: JFY49_RS11850
• Protein ID: WP_200223054.1
• Coordinates: 2411768..2413051 (+)
• Length: 428 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFY49_RS11830	2407746..2408774	+	1029	WP_086197162.1	transposase	-
JFY49_RS11835	2408840..2410006	+	1167	WP_200223051.1	RecQ family ATP-dependent DNA helicase	-
JFY49_RS11840	2410021..2410722	-	702	WP_004693132.1	IS1 family transposase	-
JFY49_RS11845	2410839..2411771	+	933	WP_200223053.1	RecQ family zinc-binding domain-containing protein	Toxin
JFY49_RS11850	2411768..2413051	+	1284	WP_200223054.1	DNA-protecting protein DprA	Antitoxin
JFY49_RS11855	2413122..2414594	-	1473	WP_195728700.1	serine/threonine protein kinase	-
JFY49_RS11860	2414591..2415145	-	555	WP_200223056.1	hypothetical protein	-
JFY49_RS11865	2415138..2416823	-	1686	WP_200223057.1	ATP-binding protein	-
JFY49_RS11870	2416825..2417961	-	1137	WP_200223058.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2410021..2455485	45464

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Phosphoribosyltransferase domain (216-297)

Antitoxin

• DNA recombination-mediator protein A (86-407)

Sequences

Toxin

Protein

• Length: 311 a.a.
• Molecular weight: 35184.17 Da
• Isoelectric Point: 8.3841

>T185582 WP_200223053.1 NZ_CP067019:2410839-2411771 [Acinetobacter sp. CS-2]
MPAKRIEHALKYLRTENPSPVSSSTGKSWSRNPVHYKLNTDHISKITAIREQEWQQMLQFINTDKCYMHLVREYLDDKNT
DKCGICSNCISEPLIDIKINSNLANKAASFIKHTEQPIEPRKQIATSNEEHINTFKIYTLPRQLGSLSAQEGRVLSRWGD
AGWGHLVKEGKEKNYFSDELVNAVADMITQRWKPSPTPQWICCVPSLNHKTLVPDFAAKLANKLGIPFIDVISKIKENEP
QKFQNNRFHQCKNLDGVFEISSKIPNSPVLLIDDMVDSRWTFTVIAALLRQHGSGEVFPVALASTSVNES

Nucleotide

• Length: 933 bp

>T185582 NZ_CP088922:c460679-460365 [Rhodanobacter denitrificans]
ATGATCTTTGTTGAGACGCCAATCTTCACTGCCCAGATCAAGGATCTGCTGAGCGATGATGATTACGGGGCGTTCCAGCG
CTATCTAGCCGAGAATCCGGAGGCTGGCGACGTCATCAAGGAAACCGGCGGACTACGCAAGATCCGCGTGGCGGCGAAGG
GTCACGGCAAGAGCGGCGGCGCGCGAGTGATCTACTACTACTTCGTTTCTGCCTCGCGTATCGCCATGGTTTTCGCCTAT
CCGAAGAACGTACAAGAAAATCTGACGCCTGCGCAAAAAGCAGCACTAAAGAAAGTCATAGAGCAGTGGAGATAA

Antitoxin

Protein

• Length: 428 a.a.
• Molecular weight: 47895.50 Da
• Isoelectric Point: 8.7693

>AT185582 WP_200223054.1 NZ_CP067019:2411768-2413051 [Acinetobacter sp. CS-2]
MNLSKSSQAIILLTSYFTKANDSEHKPLTPTEWGRFAKWLHENQHTPEDLLTREVKDILIEWQDPKISSTRLLYLLGRGH
SMALNLEKWSRSGLWVITRADSEYPWRLKQRLKQDAPPVLFGCGSKELLNYPGLAVVGSRSANVSDLKYAETIGAKASFE
SVSIISGGAKGIDESAMLGAVNNHGMTVGVMADSLLKHITSKKWRSALMNEQAVLISPFYPEAGFSTGNAMARNKYIYCL
ADSSLVVHSGLKGGTIAGAQENLRKGWVPIYIKPNDDQNSANTFLINQGGRPINTTLDNLSIIEHLFKLDLPIESHPPVD
VINHQIDMFNPNPNPNPNPNPNPNPNPNPNPNPNPNPNPNPKDFVKNFDFYNYFLDFLREANLDESTVDEIIQHSKLHKS
QVNEWLKIAISERKIQKMNKPVRYKLL

Nucleotide

• Length: 1284 bp

>AT185582 NZ_CP088922:c460350-460072 [Rhodanobacter denitrificans]
ATGTTCGACAACCTGATGGAAAGCGTGACCCAGATGGACGAGATTGTCCGGGGTGAGCGCCAGCCGTCGCGCGAGGTCCA
TATCGACGCGCTGGCCGTCAAGGAGATCCGCCGCGCCACTGGACTGTCACAGGCCAAGTTCGCCGGCATCGTCGACGTGC
AGGTCGGCACTCTTCGCAACTGGGAGCAGGGCAGGCGTGAACCCACTGGCCCAGCCAAGGCGCTACTGCGCGCGATCAGC
AAGGACCCCAAGCACGTATTGGAGGCGTTGGCCGACTGA