Detailed information of TA system TA185572

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4556253..4556619
• Replicon: chromosome
• Accession: NZ_CP067006
• Organism: Xanthomonas campestris pv. campestris strain 54-2

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: G0CKD4
• Locus tag: JH269_RS19915
• Protein ID: WP_011270059.1
• Coordinates: 4556253..4556387 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: JH269_RS19920
• Protein ID: WP_267314524.1
• Coordinates: 4556467..4556619 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JH269_RS19895 (JH269_19830)	4551516..4553168	-	1653	WP_267315112.1	M28 family metallopeptidase	-
JH269_RS19900 (JH269_19835)	4553333..4554277	-	945	WP_267314523.1	MBL fold metallo-hydrolase	-
JH269_RS19905 (JH269_19840)	4554361..4555650	-	1290	WP_029217012.1	tryptophan--tRNA ligase	-
JH269_RS19910 (JH269_19845)	4555810..4556019	-	210	WP_011038998.1	CsbD family protein	-
JH269_RS19915 (JH269_19850)	4556253..4556387	-	135	WP_011270059.1	entericidin A/B family lipoprotein	Toxin
JH269_RS19920 (JH269_19855)	4556467..4556619	-	153	WP_267314524.1	entericidin A/B family lipoprotein	Antitoxin
JH269_RS19925 (JH269_19860)	4556730..4557653	-	924	WP_040942405.1	arginase	-
JH269_RS19930 (JH269_19865)	4557967..4558428	+	462	WP_228422658.1	roadblock/LC7 domain-containing protein	-
JH269_RS19935 (JH269_19870)	4558511..4558870	+	360	WP_011039002.1	hypothetical protein	-
JH269_RS19940 (JH269_19875)	4558973..4559890	+	918	WP_267314525.1	hypothetical protein	-
JH269_RS19945 (JH269_19880)	4559887..4560429	+	543	WP_012439507.1	GTPase	-
JH269_RS19950 (JH269_19885)	4560764..4561447	+	684	WP_011039005.1	dTMP kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4431.27 Da
• Isoelectric Point: 9.3487

>T185572 WP_011270059.1 NZ_CP067006:c4556387-4556253 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Nucleotide

• Length: 135 bp

>T185572 NZ_CP088919:c3021800-3021624 [Rhodanobacter denitrificans]
ATGAAGTACAGCGAGTTCCAGCGGTGGCTCAGGCAGCAGGGAGTGAGCTTCGAGCCCGGCAAGGGCAGCCACCAGCTGGC
GCGCTACAGAGGCCGGACTTCCGTCTTTCCCTTCCACGGATCGAAAGAGATGCCCGAGCCGCTGCGCAAGAAGATCCTGA
AGGACCTGGGTCTTTGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5172.16 Da
• Isoelectric Point: 8.7942

>AT185572 WP_267314524.1 NZ_CP067006:c4556619-4556467 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGNKVEKTADKCSDGKC

Nucleotide

• Length: 153 bp

>AT185572 NZ_CP088919:c3021591-3021172 [Rhodanobacter denitrificans]
ATGAAATACCCCGTCAAGCTGACCCGTGCCGATAGCGTGGTGATGGTGACCTGTCCGGACCTGCCGGAGTTTTCCAGCGT
CGGCGACACCGAGGGCGAGGCTCTGCGCGAAGCCGTCGACGGTATCGAAACCACGCTGCAGGCGTACATGCAAGACCGGC
GTGACATTCCGCCGCCGGGCGCGCGCAAGCGCGGCCAGCGGCTGGTGGAGCTGCCGCCGCTGGCGGTGGCCAAGCTCGGT
CTGTACCGGGCCATGCGCGAACAGGGGTTGCGCAAGGCTGACCTGGCCCGCCGGCTCGACGTGCATCTGCCCCAGGTCGA
CCGCCTGCTCGACCTGCGCCACAGCTCGAAGCTGGAACAGGTGGAGGCGGCGCTCAACGCGTTGGGCTACCGGATCGAAC
TGGCGGTGCTGGCGGCGTAG

Structures

Toxin

• AlphaFold DB: A0A0H2XDQ0