Detailed information of TA system TA185570

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4708474..4708840
• Replicon: chromosome
• Accession: NZ_CP067005
• Organism: Xanthomonas campestris pv. campestris strain 54-3

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: G0CKD4
• Locus tag: JH259_RS20550
• Protein ID: WP_011270059.1
• Coordinates: 4708474..4708608 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: JH259_RS20555
• Protein ID: WP_267314524.1
• Coordinates: 4708688..4708840 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JH259_RS20530 (JH259_20490)	4703737..4705389	-	1653	WP_267315112.1	M28 family metallopeptidase	-
JH259_RS20535 (JH259_20495)	4705554..4706498	-	945	WP_267314523.1	MBL fold metallo-hydrolase	-
JH259_RS20540 (JH259_20500)	4706582..4707871	-	1290	WP_029217012.1	tryptophan--tRNA ligase	-
JH259_RS20545 (JH259_20505)	4708031..4708240	-	210	WP_011038998.1	CsbD family protein	-
JH259_RS20550 (JH259_20510)	4708474..4708608	-	135	WP_011270059.1	entericidin A/B family lipoprotein	Toxin
JH259_RS20555 (JH259_20515)	4708688..4708840	-	153	WP_267314524.1	entericidin A/B family lipoprotein	Antitoxin
JH259_RS20560 (JH259_20520)	4708951..4709874	-	924	WP_040942405.1	arginase	-
JH259_RS20565 (JH259_20525)	4710188..4710649	+	462	WP_228422658.1	roadblock/LC7 domain-containing protein	-
JH259_RS20570 (JH259_20530)	4710732..4711091	+	360	WP_011039002.1	hypothetical protein	-
JH259_RS20575 (JH259_20535)	4711194..4712111	+	918	WP_267314525.1	hypothetical protein	-
JH259_RS20580 (JH259_20540)	4712108..4712650	+	543	WP_012439507.1	GTPase	-
JH259_RS20585 (JH259_20545)	4712985..4713668	+	684	WP_011039005.1	dTMP kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4431.27 Da
• Isoelectric Point: 9.3487

>T185570 WP_011270059.1 NZ_CP067005:c4708608-4708474 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Nucleotide

• Length: 135 bp

>T185570 NZ_CP088919:700766-701047 [Rhodanobacter denitrificans]
ATGACCATCCAGTCGTTCCGCTGCAAGGATACGCAGGCGCTGTTCGAGCGACGCCGGGTGCGGCGCTTTCTGGTGATCGA
GGCGGCGGCGCGGCGCAAGCTGGAGCTGTTGAATGCGGCGACCCAACTGGACTATCTGCGGGTGCCGCCCGGCAATCGAC
TGGAAGCCTTGGCCGGCGATCGCAAGGGTCAGCACAGCATTCGTGTGAATGACCAGTTCCGGCTGTGCTTCGTGTGGACC
GCCGACGGCCCGGGCCTGGTCGAGATCGTCGATTATCACTGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5172.16 Da
• Isoelectric Point: 8.7942

>AT185570 WP_267314524.1 NZ_CP067005:c4708840-4708688 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGNKVEKTADKCSDGKC

Nucleotide

• Length: 153 bp

>AT185570 NZ_CP088919:701057-701356 [Rhodanobacter denitrificans]
ATGCCCCGCAAACTGCCACCCATCCACCCCGGCGAGATCCTGCGCGAGGAATACATGCTGCCGCTGGAGCTGTCGTCCAA
CGCGCTGGCCCGCGCCCTCGAAGTCACGCCTGCACGTATCAACGAGATCGTGCGCGAGCGGCGCGGCATCAGCGCCGATA
CCGCGCTGCGGCTGGCGCGCTATTTCGGCAATGACGCGCAGAGCTGGCTGAACCTGCAGCAGCGCTACGACATCGAGTGC
GCGCAGGACAGCATCGGCGGCGCACTGAGGAAAATCACGCCCTATCAGGCAGCCGCCTAG

Structures

Toxin

• AlphaFold DB: A0A0H2XDQ0