185568

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4656591..4656957 Replicon chromosome
Accession NZ_CP067004
Organism Xanthomonas campestris pv. campestris strain 30-1

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH303_RS20280 Protein ID WP_011270059.1
Coordinates 4656591..4656725 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH303_RS20285 Protein ID WP_011038999.1
Coordinates 4656805..4656957 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH303_RS20260 (JH303_20245) 4651856..4653508 - 1653 WP_274498596.1 M28 family metallopeptidase -
JH303_RS20265 (JH303_20250) 4653673..4654617 - 945 WP_040942012.1 MBL fold metallo-hydrolase -
JH303_RS20270 (JH303_20255) 4654701..4655990 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH303_RS20275 (JH303_20260) 4656150..4656359 - 210 WP_011038998.1 CsbD family protein -
JH303_RS20280 (JH303_20265) 4656591..4656725 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH303_RS20285 (JH303_20270) 4656805..4656957 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH303_RS20290 (JH303_20275) 4657068..4657991 - 924 WP_274497878.1 arginase -
JH303_RS20295 (JH303_20280) 4658305..4658766 + 462 WP_228422658.1 roadblock/LC7 domain-containing protein -
JH303_RS20300 (JH303_20285) 4658849..4659208 + 360 WP_011039002.1 hypothetical protein -
JH303_RS20305 (JH303_20290) 4659311..4660228 + 918 WP_014506231.1 hypothetical protein -
JH303_RS20310 (JH303_20295) 4660225..4660767 + 543 WP_012439507.1 GTPase -
JH303_RS20315 (JH303_20300) 4661102..4661785 + 684 WP_228422659.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185568 WP_011270059.1 NZ_CP067004:c4656725-4656591 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185568 NZ_CP088918:943817-944131 [Rhodanobacter denitrificans]
ATGATCTTTGTTGAGACGCCAATCTTCACTGCCCAGATCAAGGATCTGCTGAGCGATGATGATTACGGGGCGTTCCAGCG
CTATCTAGCCGAGAATCCGGAGGCTGGCGACGTCATCAAGGAAACCGGCGGACTACGCAAGATCCGCGTGGCGGCGAAGG
GTCACGGCAAGAGCGGCGGCGCGCGAGTGATCTACTACTACTTCGTTTCTGCCTCGCGTATCGCCATGGTTTTCGCCTAT
CCGAAGAACGTACAAGAAAATCTGACGCCTGCGCAAAAAGCAGCACTAAAGAAAGTCATAGAGCAGTGGAGATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185568 WP_011038999.1 NZ_CP067004:c4656957-4656805 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185568 NZ_CP088918:944146-944424 [Rhodanobacter denitrificans]
ATGTTCGACAACCTGATGGAAAGCGTGACCCAGATGGACGAGATTGTCCGGGGTGAGCGCCAGCCGTCGCGCGAGGTCCA
TATCGACGCGCTGGCCGTCAAGGAGATCCGCCGCGCCACTGGACTGTCACAGGCCAAGTTCGCCGGCATCGTCGACGTGC
AGGTCGGCACTCTTCGCAACTGGGAGCAGGGCAGGCGTGAACCCACTGGCCCAGCCAAGGCGCTACTGCGCGCGATCAGC
AAGGACCCCAAGCACGTATTGGAGGCGTTGGCCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References