Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4823657..4824023 Replicon chromosome
Accession NZ_CP067001
Organism Xanthomonas campestris pv. campestris strain 40-2

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH287_RS20900 Protein ID WP_011270059.1
Coordinates 4823889..4824023 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH287_RS20895 Protein ID WP_011038999.1
Coordinates 4823657..4823809 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH287_RS20865 (JH287_20835) 4818830..4819513 - 684 WP_011039005.1 dTMP kinase -
JH287_RS20870 (JH287_20840) 4819847..4820389 - 543 WP_012439507.1 GTPase -
JH287_RS20875 (JH287_20845) 4820386..4821303 - 918 WP_274496807.1 hypothetical protein -
JH287_RS20880 (JH287_20850) 4821406..4821765 - 360 WP_011039002.1 hypothetical protein -
JH287_RS20885 (JH287_20855) 4821848..4822309 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH287_RS20890 (JH287_20860) 4822623..4823546 + 924 WP_040942405.1 arginase -
JH287_RS20895 (JH287_20865) 4823657..4823809 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH287_RS20900 (JH287_20870) 4823889..4824023 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH287_RS20905 (JH287_20875) 4824257..4824466 + 210 WP_011038998.1 CsbD family protein -
JH287_RS20910 (JH287_20880) 4824626..4825915 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH287_RS20915 (JH287_20885) 4825999..4826943 + 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH287_RS20920 (JH287_20890) 4827108..4828760 + 1653 WP_043890286.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185564 WP_011270059.1 NZ_CP067001:4823889-4824023 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185564 NZ_CP088909:267887-268243 [Rhodococcus qingshengii]
ATGATTCGCCGCGCGCACATTCACTGGGTGGATCTCGATCCGGCGCAGGGCAGTGAAGCGGCGAAACGACGACCGGCGGT
GGTGGTGAGCAACGACCGGGCCAACGCTACTGCAGAAAATCTCGGCAGGGGCGTGATCACCGTGGTTCCGTTGACTACCA
ATACCGCGCACGTGTTTCCGTTTCAGGTGATTGTCGAGTCCGACGAGTCAGGTTTGGCGCGAGCGTCGAAAGCGCAAGCG
GAGCAAGTGCGTTCGGTATCGGTTCGGCGTCTGGATCCTGAACCTGTCGGCAAGGTCGGGATGGAGACTTTCGCCGCACT
CGAGGACGCGCTGCGGCTGCACCTCGATCTGCAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185564 WP_011038999.1 NZ_CP067001:4823657-4823809 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185564 NZ_CP088909:267678-267890 [Rhodococcus qingshengii]
ATGACCACGAAATTTACCATAAGTCTGCCTGACGAGGATGCGCACCTACTCGACGAGTATGTGCGTGATCACGGACTTCG
TGGCCGGTCGGCAGGAATTCGAGCCGCACTCCGCCTACTCTCGACGTCCGGACTCGAACGTGACTACGCTGCAGCGTTTG
CTGAAGGTGACGTAGATGAAGTGTGGGACGCTGTCACGGCAGACACCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References