185561

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1373064..1373430 Replicon chromosome
Accession NZ_CP067000
Organism Xanthomonas campestris pv. campestris strain 29-5

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH291_RS06360 Protein ID WP_011270059.1
Coordinates 1373064..1373198 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH291_RS06365 Protein ID WP_011038999.1
Coordinates 1373278..1373430 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH291_RS06340 (JH291_06335) 1368327..1369979 - 1653 WP_043890286.1 M28 family metallopeptidase -
JH291_RS06345 (JH291_06340) 1370144..1371088 - 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH291_RS06350 (JH291_06345) 1371172..1372461 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH291_RS06355 (JH291_06350) 1372621..1372830 - 210 WP_011038998.1 CsbD family protein -
JH291_RS06360 (JH291_06355) 1373064..1373198 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH291_RS06365 (JH291_06360) 1373278..1373430 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH291_RS06370 (JH291_06365) 1373541..1374464 - 924 WP_040942405.1 arginase -
JH291_RS06375 (JH291_06370) 1374778..1375239 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH291_RS06380 (JH291_06375) 1375322..1375681 + 360 WP_011039002.1 hypothetical protein -
JH291_RS06385 (JH291_06380) 1375784..1376701 + 918 WP_274496807.1 hypothetical protein -
JH291_RS06390 (JH291_06385) 1376698..1377240 + 543 WP_012439507.1 GTPase -
JH291_RS06395 (JH291_06390) 1377574..1378257 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185561 WP_011270059.1 NZ_CP067000:c1373198-1373064 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185561 NZ_CP088902:c49046-48630 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGAAGAAAATGTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCCGAAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCACCGTATTGTGGTCTCGGCCATCACCTACTCAGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGTCACATTGAACTGGTTGACGCGTTCTGCGCCCGCCTCGATGCTATCCTGCCCTGGGACCGGGCC
GCGGTGAACGCCACCACGGAGATTAAGGTGGCGCTACGCCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCGATCGC
CGGGCACGCTATTGCCGCCGGCGCGGTACTGGTGACAAATAATACGCGGGAGTTTGAGCGGGTGCCGGGTCTTGTTCTGG
AAGACTGGGGAAGATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185561 WP_011038999.1 NZ_CP067000:c1373430-1373278 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185561 NZ_CP088902:c49273-49043 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAGAACCGTATCTATTTTTAAAAACGGCAACAACCGCGCCATCCGCCTTCCCCGCGATCTGGATTTTGATGGAGTGAG
CGAGCTGGAAATCGTCCGGGAAGGGGACAGCATCATCCTGCGCCCTGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTCG
AAAAAGCTGACCCGGGCTTTATGGCGGAGCGTGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References