Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4968883..4969289 Replicon chromosome
Accession NZ_CP066997
Organism Xanthomonas campestris pv. campestris strain 33-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH288_RS21660 Protein ID WP_267129426.1
Coordinates 4969134..4969289 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH288_RS21655 Protein ID WP_070694028.1
Coordinates 4968883..4969137 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH288_RS21630 (JH288_21590) 4964385..4965224 + 840 WP_014509612.1 SDR family oxidoreductase -
JH288_RS21635 (JH288_21595) 4965368..4966633 + 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH288_RS21640 (JH288_21600) 4966651..4967180 - 530 Protein_4174 hypothetical protein -
JH288_RS21645 (JH288_21605) 4967437..4967643 + 207 WP_014509615.1 hypothetical protein -
JH288_RS21650 (JH288_21610) 4967630..4968745 + 1116 WP_274399598.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH288_RS21655 (JH288_21615) 4968883..4969137 + 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH288_RS21660 (JH288_21620) 4969134..4969289 + 156 WP_267129426.1 hypothetical protein Toxin
JH288_RS21665 (JH288_21625) 4969344..4970312 - 969 WP_274399603.1 DUF2971 domain-containing protein -
JH288_RS21670 (JH288_21630) 4970475..4972094 + 1620 WP_274399604.1 alpha/beta hydrolase-fold protein -
JH288_RS21675 (JH288_21635) 4972655..4973056 - 402 WP_016945062.1 DUF2384 domain-containing protein -
JH288_RS21680 (JH288_21640) 4973373..4973828 + 456 WP_162808719.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185558 WP_267129426.1 NZ_CP066997:4969134-4969289 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185558 NZ_CP088901:4667545-4667856 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185558 WP_070694028.1 NZ_CP066997:4968883-4969137 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185558 NZ_CP088901:4667853-4668299 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAATCACTCAAC
CAACACCTGGAGAAAACACCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTTAAACTACCAGCGGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References