185557

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4636156..4636519 Replicon chromosome
Accession NZ_CP066997
Organism Xanthomonas campestris pv. campestris strain 33-1

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH288_RS20300 Protein ID WP_011270059.1
Coordinates 4636156..4636290 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH288_RS20305 Protein ID WP_011038999.1
Coordinates 4636367..4636519 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH288_RS20280 (JH288_20250) 4631420..4633072 - 1653 WP_057673525.1 M28 family metallopeptidase -
JH288_RS20285 (JH288_20255) 4633237..4634181 - 945 WP_274399398.1 MBL fold metallo-hydrolase -
JH288_RS20290 (JH288_20260) 4634265..4635554 - 1290 WP_274399400.1 tryptophan--tRNA ligase -
JH288_RS20295 (JH288_20265) 4635714..4635923 - 210 WP_011038998.1 CsbD family protein -
JH288_RS20300 (JH288_20270) 4636156..4636290 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH288_RS20305 (JH288_20275) 4636367..4636519 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH288_RS20310 (JH288_20280) 4636630..4637553 - 924 WP_011039000.1 arginase -
JH288_RS20315 (JH288_20285) 4637867..4638328 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH288_RS20320 (JH288_20290) 4638411..4638770 + 360 WP_011039002.1 hypothetical protein -
JH288_RS20325 (JH288_20295) 4638873..4639790 + 918 WP_014506231.1 hypothetical protein -
JH288_RS20330 (JH288_20300) 4639787..4640329 + 543 WP_011039004.1 GTPase -
JH288_RS20335 (JH288_20305) 4640664..4641347 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185557 WP_011270059.1 NZ_CP066997:c4636290-4636156 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185557 NZ_CP088901:c4666312-4666001 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185557 WP_011038999.1 NZ_CP066997:c4636519-4636367 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185557 NZ_CP088901:c4666000-4665710 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAACCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAGC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References