Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 361454..361820 Replicon chromosome
Accession NZ_CP066996
Organism Xanthomonas campestris pv. campestris strain 33-2

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH255_RS01510 Protein ID WP_011270059.1
Coordinates 361686..361820 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH255_RS01505 Protein ID WP_011038999.1
Coordinates 361454..361606 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH255_RS01475 (JH255_01455) 356626..357309 - 684 WP_228422659.1 dTMP kinase -
JH255_RS01480 (JH255_01460) 357644..358186 - 543 WP_012439507.1 GTPase -
JH255_RS01485 (JH255_01465) 358183..359100 - 918 WP_014506231.1 hypothetical protein -
JH255_RS01490 (JH255_01470) 359203..359562 - 360 WP_011039002.1 hypothetical protein -
JH255_RS01495 (JH255_01475) 359645..360106 - 462 WP_228422658.1 roadblock/LC7 domain-containing protein -
JH255_RS01500 (JH255_01480) 360420..361343 + 924 WP_274497878.1 arginase -
JH255_RS01505 (JH255_01485) 361454..361606 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH255_RS01510 (JH255_01490) 361686..361820 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH255_RS01515 (JH255_01495) 362052..362261 + 210 WP_011038998.1 CsbD family protein -
JH255_RS01520 (JH255_01500) 362421..363710 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH255_RS01525 (JH255_01505) 363794..364738 + 945 WP_040942012.1 MBL fold metallo-hydrolase -
JH255_RS01530 (JH255_01510) 364903..366555 + 1653 WP_274498596.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185554 WP_011270059.1 NZ_CP066996:361686-361820 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185554 NZ_CP088901:3723446-3723721 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAATGCCTCCGGCGTTAGCGTCCGCCATATCAACAGCGAAACCTGCATGACCGCCTGTTACTCACAAATCCCCAGCCA
GCACCTTAAGGGTGACTGGCAGGAAGAAGCGGGATTTGAGACCGGGCACGGCGTCACCGTGAAGATCTCCGAGGGGTGTT
TGATCCTGATTGCAGAGACGGACGAAGTGAGGGATCTACGGAAGGAGCTTTATCAGGTGAAAAAGTCGATGAAGCATATT
AAGGCGGGGGTAAATAATGTGGTGAACGGGGATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185554 WP_011038999.1 NZ_CP066996:361454-361606 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185554 NZ_CP088901:c3723711-3723289 [Salmonella enterica subsp. enterica serovar Muenchen]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTAACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References