185550

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 361240..361606 Replicon chromosome
Accession NZ_CP066994
Organism Xanthomonas campestris pv. campestris strain 33-5

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH276_RS01500 Protein ID WP_011270059.1
Coordinates 361472..361606 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH276_RS01495 Protein ID WP_011038999.1
Coordinates 361240..361392 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH276_RS01465 (JH276_01450) 356412..357095 - 684 WP_228422659.1 dTMP kinase -
JH276_RS01470 (JH276_01455) 357430..357972 - 543 WP_012439507.1 GTPase -
JH276_RS01475 (JH276_01460) 357969..358886 - 918 WP_014506231.1 hypothetical protein -
JH276_RS01480 (JH276_01465) 358989..359348 - 360 WP_011039002.1 hypothetical protein -
JH276_RS01485 (JH276_01470) 359431..359892 - 462 WP_228422658.1 roadblock/LC7 domain-containing protein -
JH276_RS01490 (JH276_01475) 360206..361129 + 924 WP_274497878.1 arginase -
JH276_RS01495 (JH276_01480) 361240..361392 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH276_RS01500 (JH276_01485) 361472..361606 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH276_RS01505 (JH276_01490) 361838..362047 + 210 WP_011038998.1 CsbD family protein -
JH276_RS01510 (JH276_01495) 362207..363496 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH276_RS01515 (JH276_01500) 363580..364524 + 945 WP_040942012.1 MBL fold metallo-hydrolase -
JH276_RS01520 (JH276_01505) 364689..366341 + 1653 WP_274498596.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185550 WP_011270059.1 NZ_CP066994:361472-361606 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185550 NZ_CP088901:854959-855372 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTAATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGTTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185550 WP_011038999.1 NZ_CP066994:361240-361392 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185550 NZ_CP088901:854712-854978 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References