185549

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4667825..4668191 Replicon chromosome
Accession NZ_CP066993
Organism Xanthomonas campestris pv. campestris strain 42-3

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH268_RS20360 Protein ID WP_011270059.1
Coordinates 4667825..4667959 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH268_RS20365 Protein ID WP_011038999.1
Coordinates 4668039..4668191 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH268_RS20340 (JH268_20270) 4663090..4664742 - 1653 WP_274498596.1 M28 family metallopeptidase -
JH268_RS20345 (JH268_20275) 4664907..4665851 - 945 WP_040942012.1 MBL fold metallo-hydrolase -
JH268_RS20350 (JH268_20280) 4665935..4667224 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH268_RS20355 (JH268_20285) 4667384..4667593 - 210 WP_011038998.1 CsbD family protein -
JH268_RS20360 (JH268_20290) 4667825..4667959 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH268_RS20365 (JH268_20295) 4668039..4668191 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH268_RS20370 (JH268_20300) 4668302..4669225 - 924 WP_274497878.1 arginase -
JH268_RS20375 (JH268_20305) 4669539..4670000 + 462 WP_228422658.1 roadblock/LC7 domain-containing protein -
JH268_RS20380 (JH268_20310) 4670083..4670442 + 360 WP_011039002.1 hypothetical protein -
JH268_RS20385 (JH268_20315) 4670545..4671462 + 918 WP_014506231.1 hypothetical protein -
JH268_RS20390 (JH268_20320) 4671459..4672001 + 543 WP_012439507.1 GTPase -
JH268_RS20395 (JH268_20325) 4672336..4673019 + 684 WP_228422659.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185549 WP_011270059.1 NZ_CP066993:c4667959-4667825 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185549 NZ_CP088901:311879-312247 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTATCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCACTATATCCCGTGGGTATATCTTCAATGATGGTAACAAACGCACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAACAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185549 WP_011038999.1 NZ_CP066993:c4668191-4668039 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185549 NZ_CP088901:311661-311882 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGCGCGGTAACGGCGGGCCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGAAGCTGGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References