185547

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4667585..4667951 Replicon chromosome
Accession NZ_CP066992
Organism Xanthomonas campestris pv. campestris strain 66-2

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH285_RS20370 Protein ID WP_011270059.1
Coordinates 4667585..4667719 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH285_RS20375 Protein ID WP_011038999.1
Coordinates 4667799..4667951 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH285_RS20350 (JH285_20280) 4662850..4664502 - 1653 WP_274498596.1 M28 family metallopeptidase -
JH285_RS20355 (JH285_20285) 4664667..4665611 - 945 WP_040942012.1 MBL fold metallo-hydrolase -
JH285_RS20360 (JH285_20290) 4665695..4666984 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH285_RS20365 (JH285_20295) 4667144..4667353 - 210 WP_011038998.1 CsbD family protein -
JH285_RS20370 (JH285_20300) 4667585..4667719 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH285_RS20375 (JH285_20305) 4667799..4667951 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH285_RS20380 (JH285_20310) 4668062..4668985 - 924 WP_274497878.1 arginase -
JH285_RS20385 (JH285_20315) 4669299..4669760 + 462 WP_228422658.1 roadblock/LC7 domain-containing protein -
JH285_RS20390 (JH285_20320) 4669843..4670202 + 360 WP_011039002.1 hypothetical protein -
JH285_RS20395 (JH285_20325) 4670305..4671222 + 918 WP_014506231.1 hypothetical protein -
JH285_RS20400 (JH285_20330) 4671219..4671761 + 543 WP_012439507.1 GTPase -
JH285_RS20405 (JH285_20335) 4672096..4672779 + 684 WP_228422659.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185547 WP_011270059.1 NZ_CP066992:c4667719-4667585 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185547 NZ_CP088896:c7391-6984 [Acinetobacter baumannii]
ATGGAATATCTACTTGATACAAATATCGTGGGCTATCTTTTACAAGGTGTTGCCAGTAATAAGCTGAAGAACAAGCTGAT
GATGGTTAATCCTGATAGTGTATTTATTTCACAGATTACTCATGCTGAGATTGTTTATGGCCTAGAAAAAGGTGGGAATA
TTCCCAAGCATATTGATCGTGTAAACTCTTTTTTAGAAACCTTAAGTATTTTAGATTGGGATGATCAGTGCGCTCATGCT
TACGGCAAGGTTCGTAATGAATTACGTCTACAGGGTGTCACTGTACAGTCAATGGATTTGATGATTGGTGCTCATGCACT
TGGTCATCATCTTATTTTAGTCAGCAATGATCATATTTTTGATCATTTCAAACAATTTGGACTAGTTTTAGAAAACTGGC
AAATTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185547 WP_011038999.1 NZ_CP066992:c4667951-4667799 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185547 NZ_CP088896:c7630-7391 [Acinetobacter baumannii]
ATGAATCATACCGCAAAAGTTTTTATGAATGGTCAAAGCCAAGCAGTACGCCTGCCGAAACAATTTCGTTTTGAAAGCAA
AACTGTTTATGTCAGACGAAATACTAAAGGTGAAGTAATCCTTTCTGAAAAACCTCGGACATGGGCTGATTTTTTTGAGG
AAAATACTGATATGTCAGGATTTGAGACATTAATGGCTGATCGTGAACAGGACATACCAATTGAACGAGATATTTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References