Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4976281..4976687 Replicon chromosome
Accession NZ_CP066990
Organism Xanthomonas campestris pv. campestris strain 42-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH289_RS21710 Protein ID WP_267129426.1
Coordinates 4976532..4976687 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH289_RS21705 Protein ID WP_070694028.1
Coordinates 4976281..4976535 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH289_RS21680 (JH289_21625) 4971783..4972622 + 840 WP_014509612.1 SDR family oxidoreductase -
JH289_RS21685 (JH289_21630) 4972766..4974031 + 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH289_RS21690 (JH289_21635) 4974049..4974578 - 530 Protein_4183 hypothetical protein -
JH289_RS21695 (JH289_21640) 4974835..4975041 + 207 WP_014509615.1 hypothetical protein -
JH289_RS21700 (JH289_21645) 4975028..4976143 + 1116 WP_274399598.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH289_RS21705 (JH289_21650) 4976281..4976535 + 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH289_RS21710 (JH289_21655) 4976532..4976687 + 156 WP_267129426.1 hypothetical protein Toxin
JH289_RS21715 (JH289_21660) 4976742..4977710 - 969 WP_274399603.1 DUF2971 domain-containing protein -
JH289_RS21720 (JH289_21665) 4977873..4979492 + 1620 WP_274399604.1 alpha/beta hydrolase-fold protein -
JH289_RS21725 (JH289_21670) 4980053..4980454 - 402 WP_016945062.1 DUF2384 domain-containing protein -
JH289_RS21730 (JH289_21675) 4980771..4981226 + 456 WP_162808719.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185545 WP_267129426.1 NZ_CP066990:4976532-4976687 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185545 NZ_CP088895:3173814-3173993 [Acinetobacter baumannii]
ATGAGCTTCAACGAGTTTAAACGATGGCTAATTGCACAGGGAGTTATCTTTGTGCGTAAAGGTAAGGGATCACATATGAT
TATTGAATTTAACGGTAAGAAGACTGTTTTCCCTAACCACGGGAAAAAAGAAATTCCTGAAGGCACTCGTTTAAAGATCA
AAAAGGATTTGGGGCTTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185545 WP_070694028.1 NZ_CP066990:4976281-4976535 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185545 NZ_CP088895:3174079-3174492 [Acinetobacter baumannii]
ATGAAATGTTATGTCAGTATTCATAGGGAGGGAGAGGCTTTTATAGTCAGCTCAAGTGAACTCCCTGAACTAAATAGTGT
AGGCTATACTTTAGAAGAAGCTTTATCAGAAGCTTTGGATGGTATAGAAACAGTATTCGAAATTTATATGGATGAGCGTA
AAGCCATCCCATTACCATCAAAAGGTAAGAAAGGTGAATATGCAGTTCATCTTCCAGTTCGAGTCGCTGCTAAGGTACGT
TTATATAATGAGATGATCTCACAAAACGTTACTAAAGCTGAATTAGCTCGTCGCTTGGGGTGGTTACAGAAGCAAGCCGA
TCGTTTGCTTTCATTAAAGCATTCAACAAAACTAGAATCGATTGAAAGTGCCTTCCAAGCATTAGGCAAGGATCTCGATA
TAGTTATCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References