185544

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4648234..4648597 Replicon chromosome
Accession NZ_CP066990
Organism Xanthomonas campestris pv. campestris strain 42-1

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH289_RS20350 Protein ID WP_011270059.1
Coordinates 4648234..4648368 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH289_RS20355 Protein ID WP_011038999.1
Coordinates 4648445..4648597 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH289_RS20330 (JH289_20290) 4643498..4645150 - 1653 WP_057673525.1 M28 family metallopeptidase -
JH289_RS20335 (JH289_20295) 4645315..4646259 - 945 WP_274399398.1 MBL fold metallo-hydrolase -
JH289_RS20340 (JH289_20300) 4646343..4647632 - 1290 WP_274399400.1 tryptophan--tRNA ligase -
JH289_RS20345 (JH289_20305) 4647792..4648001 - 210 WP_011038998.1 CsbD family protein -
JH289_RS20350 (JH289_20310) 4648234..4648368 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH289_RS20355 (JH289_20315) 4648445..4648597 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH289_RS20360 (JH289_20320) 4648708..4649631 - 924 WP_011039000.1 arginase -
JH289_RS20365 (JH289_20325) 4649945..4650406 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH289_RS20370 (JH289_20330) 4650489..4650848 + 360 WP_011039002.1 hypothetical protein -
JH289_RS20375 (JH289_20335) 4650951..4651868 + 918 WP_014506231.1 hypothetical protein -
JH289_RS20380 (JH289_20340) 4651865..4652407 + 543 WP_011039004.1 GTPase -
JH289_RS20385 (JH289_20345) 4652742..4653425 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185544 WP_011270059.1 NZ_CP066990:c4648368-4648234 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185544 NZ_CP088895:526693-527082 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAACTTGCAAAAATTGCCTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCCATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185544 WP_011038999.1 NZ_CP066990:c4648597-4648445 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185544 NZ_CP088895:526429-526686 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References