Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4967740..4968146 Replicon chromosome
Accession NZ_CP066988
Organism Xanthomonas campestris pv. campestris strain 42-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH305_RS21715 Protein ID WP_267129426.1
Coordinates 4967991..4968146 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH305_RS21710 Protein ID WP_070694028.1
Coordinates 4967740..4967994 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH305_RS21685 (JH305_21620) 4963242..4964081 + 840 WP_014509612.1 SDR family oxidoreductase -
JH305_RS21690 (JH305_21625) 4964225..4965490 + 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH305_RS21695 (JH305_21630) 4965508..4966037 - 530 Protein_4184 hypothetical protein -
JH305_RS21700 (JH305_21635) 4966294..4966500 + 207 WP_014509615.1 hypothetical protein -
JH305_RS21705 (JH305_21640) 4966487..4967602 + 1116 WP_274399598.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH305_RS21710 (JH305_21645) 4967740..4967994 + 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH305_RS21715 (JH305_21650) 4967991..4968146 + 156 WP_267129426.1 hypothetical protein Toxin
JH305_RS21720 (JH305_21655) 4968201..4969169 - 969 WP_274399603.1 DUF2971 domain-containing protein -
JH305_RS21725 (JH305_21660) 4969332..4970951 + 1620 WP_274399604.1 alpha/beta hydrolase-fold protein -
JH305_RS21730 (JH305_21665) 4971512..4971913 - 402 WP_016945062.1 DUF2384 domain-containing protein -
JH305_RS21735 (JH305_21670) 4972230..4972685 + 456 WP_162808719.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4967740..4982251 14511


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185542 WP_267129426.1 NZ_CP066988:4967991-4968146 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185542 NZ_CP088894:410564-410953 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAACTTGCAAAAATTGCCTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCCATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185542 WP_070694028.1 NZ_CP066988:4967740-4967994 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185542 NZ_CP088894:410300-410557 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References