Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4639700..4640063 Replicon chromosome
Accession NZ_CP066988
Organism Xanthomonas campestris pv. campestris strain 42-2

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH305_RS20350 Protein ID WP_011270059.1
Coordinates 4639700..4639834 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH305_RS20355 Protein ID WP_011038999.1
Coordinates 4639911..4640063 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH305_RS20330 (JH305_20280) 4634964..4636616 - 1653 WP_057673525.1 M28 family metallopeptidase -
JH305_RS20335 (JH305_20285) 4636781..4637725 - 945 WP_274399398.1 MBL fold metallo-hydrolase -
JH305_RS20340 (JH305_20290) 4637809..4639098 - 1290 WP_274399400.1 tryptophan--tRNA ligase -
JH305_RS20345 (JH305_20295) 4639258..4639467 - 210 WP_011038998.1 CsbD family protein -
JH305_RS20350 (JH305_20300) 4639700..4639834 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH305_RS20355 (JH305_20305) 4639911..4640063 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH305_RS20360 (JH305_20310) 4640174..4641097 - 924 WP_011039000.1 arginase -
JH305_RS20365 (JH305_20315) 4641411..4641872 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH305_RS20370 (JH305_20320) 4641955..4642314 + 360 WP_011039002.1 hypothetical protein -
JH305_RS20375 (JH305_20325) 4642417..4643334 + 918 WP_014506231.1 hypothetical protein -
JH305_RS20380 (JH305_20330) 4643331..4643873 + 543 WP_011039004.1 GTPase -
JH305_RS20385 (JH305_20335) 4644208..4644891 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185541 WP_011270059.1 NZ_CP066988:c4639834-4639700 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185541 NZ_CP088293:282531-282974 [Phyllobacterium sp. T1018]
GTGACGCCATATCTCCTGGACGTCAATGTGCTGATTGCCCTATTCGATCCCGCACACGTCCATCACGATCCTGCACATGA
GTGGTTTGCTGATATAGGACGGTCCAGTTGGGCCACTTGCCCAATAACCGAGAACGGTGCGATCCGTATTATCAGCAGCG
CCCGCTACCCTAACTCACCGGGCACGCCAGCCGCGGTTGTTGCGCTTCTGGCCGGATTACGTGCCATTCCGGGTCATGTC
TTTTGGCCAGATGACATCAGCTTGATGGACAATTCCATTGATCCGTCGCGGCTGTTGAATGCCGGTCAGGTCACGGATAC
ATACCTCCTGGCGCTTGCTCAGGCACACCAAGGGAAATTGGCGACCTTTGATCGGCGCCTCGTAACCGATGCGGTACGGG
ATGGCCGAAATTGTCTGCATGTCATTGGCGAACGAACCACTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185541 WP_011038999.1 NZ_CP066988:c4640063-4639911 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185541 NZ_CP088293:282304-282534 [Phyllobacterium sp. T1018]
ATGCGAACAACGCTTGCAATAGATGATGACGTCCTAGCGGCGGCCAAGGGCCTCGCGGAGCGCCAGCGCAAAACTGTAGG
TGAAGTCATATCGACACTCGCCCGCAAAGGTCTGCAAGCTCCAACGGCACGTCAAGCGACGCGAAACGGCGTGCCGCTCC
TCCCGGCAGGCACCAATTCCACGCCGGTAACGATGGAACTGGTGAACCAACTTCGCGATGAATTGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References