Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 334740..335103 Replicon chromosome
Accession NZ_CP066987
Organism Xanthomonas campestris pv. campestris strain 42-4

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH311_RS01405 Protein ID WP_011270059.1
Coordinates 334969..335103 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH311_RS01400 Protein ID WP_011038999.1
Coordinates 334740..334892 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH311_RS01370 (JH311_01355) 329912..330595 - 684 WP_050911792.1 dTMP kinase -
JH311_RS01375 (JH311_01360) 330930..331472 - 543 WP_011039004.1 GTPase -
JH311_RS01380 (JH311_01365) 331469..332386 - 918 WP_014506231.1 hypothetical protein -
JH311_RS01385 (JH311_01370) 332489..332848 - 360 WP_011039002.1 hypothetical protein -
JH311_RS01390 (JH311_01375) 332931..333392 - 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH311_RS01395 (JH311_01380) 333706..334629 + 924 WP_011039000.1 arginase -
JH311_RS01400 (JH311_01385) 334740..334892 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH311_RS01405 (JH311_01390) 334969..335103 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH311_RS01410 (JH311_01395) 335336..335545 + 210 WP_011038998.1 CsbD family protein -
JH311_RS01415 (JH311_01400) 335705..336994 + 1290 WP_274399400.1 tryptophan--tRNA ligase -
JH311_RS01420 (JH311_01405) 337078..338022 + 945 WP_274399398.1 MBL fold metallo-hydrolase -
JH311_RS01425 (JH311_01410) 338187..339839 + 1653 WP_057673525.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185538 WP_011270059.1 NZ_CP066987:334969-335103 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185538 NZ_CP088292:c1118011-1117619 [Phyllobacterium sp. T1018]
ATGACGTATTTGCTCGACACGAATGCGGTCATAGCACTTCTCAAATTCAACGATAAATTTCGCTCCAATATGATGCGACA
TTCGCCGCAGGATATCGCCATTTCAGCGATCGTGGCCCATGAACTCTACTTCGGCGCCTATAAATCTGAACGGCGGGAGA
AAAATCTTGCGGATATAGAAATCCTGCAGTTTCAAATCCTGGAATTCAGCCAAGAGGATGCCCGGTCGGCGGGTGCGCTT
CGCGCCCATCTTTCACGCGAAGGAACGCCGATCGGCCCCTATGATGTGCTCATTGCAGGACAGGCGCGCGCCCGCTCGCT
CGTCCTCGTTACCAGAAATGTTCGCGAGTTCGAGCGCATCGGCGGACTGACGATTGAAAACTGGGAAGGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185538 WP_011038999.1 NZ_CP066987:334740-334892 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185538 NZ_CP088292:c1118250-1118008 [Phyllobacterium sp. T1018]
GTGGACACAGCGAAGATTTTCTGGTCGGGACGGTCGCAAGCAGTACGCTTGCCGAAGGAGTTTCGCTTCGAGACTTCAGA
GGTGAGAATTCGCAGGCAGGGAAATGCTGTAATTCTCGAACCGATTGCGAATGATTGGGCATGGCTCAGCGAACTGTCGG
GGCACGTGGACGAAGATTTCGAGCAAGCGGCGAGCGAACAACCTGAAGCCCAGGAAAGGCCTGATCTGGACTTCTTTAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References