Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 6657..7063 Replicon chromosome
Accession NZ_CP066987
Organism Xanthomonas campestris pv. campestris strain 42-4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH311_RS00045 Protein ID WP_267129426.1
Coordinates 6657..6812 (-) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH311_RS00050 Protein ID WP_070694028.1
Coordinates 6809..7063 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH311_RS00025 (JH311_00025) 2118..2573 - 456 WP_162808719.1 hypothetical protein -
JH311_RS00030 (JH311_00030) 2890..3291 + 402 WP_016945062.1 DUF2384 domain-containing protein -
JH311_RS00035 (JH311_00035) 3852..5471 - 1620 WP_274399604.1 alpha/beta hydrolase-fold protein -
JH311_RS00040 (JH311_00040) 5634..6602 + 969 WP_274399603.1 DUF2971 domain-containing protein -
JH311_RS00045 (JH311_00045) 6657..6812 - 156 WP_267129426.1 hypothetical protein Toxin
JH311_RS00050 (JH311_00050) 6809..7063 - 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH311_RS00055 (JH311_00055) 7201..8316 - 1116 WP_274399598.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH311_RS00060 (JH311_00060) 8303..8509 - 207 WP_014509615.1 hypothetical protein -
JH311_RS00065 (JH311_00065) 8766..9295 + 530 Protein_12 hypothetical protein -
JH311_RS00070 (JH311_00070) 9313..10578 - 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH311_RS00075 (JH311_00075) 10722..11561 - 840 WP_014509612.1 SDR family oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(1-39)


Sequences


Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185537 WP_267129426.1 NZ_CP066987:c6812-6657 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185537 NZ_CP088292:c921918-921490 [Phyllobacterium sp. T1018]
ATGATCGTCCTTGATACGAATGTTATTTCCGAGCCGCTGAAACGGAGCCCGGACCCGGGGGTATTGTCGTGGCTCGATCA
ACAAGGGGCCGAAACGCTGTTTCTCACCACAACAAGCCTGTCGGAGCTTCTCCTCGGGATTGAACTCTTGCCCAAAGGCA
AGCGAAAACAAGGCCTTGATCGCGCGCTGAGCGAACTCATTTCGTACCTCTTCGGCGATCGGATCCTCGATTTTGACCGG
CAAGCGGCCTTGGTCTACGCCCCGTTGGTGAGCCAGGCGCGTTCGACCGGACGGACGATCTCAATCGCAGACGGGCAAAT
AGCTGCGGTCGCAAAGAGCCGCGGATATTCCGTCGCCTCGAGAGACACAATGCCATTCACCGCGGCCGGGCTCACGGTGA
TCAATCCATGGCAAGAAGAAAAGACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185537 WP_070694028.1 NZ_CP066987:c7063-6809 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185537 NZ_CP088292:c922154-921915 [Phyllobacterium sp. T1018]
ATGGCTGCCGTAACCATCAGGAATTTGCCGGAAGAAACGCATCGTGCGCTCAAATTGCGTGCCGCCAAACATGGCCGGAG
CACGGAGGCCGAAATTCGCGAAATTCTGGAGGAGGCGACACGCCCGAAGGATCGCTTGAAGATAGGCTCGGAACTTGCCG
CTTTCGGCCGCCGCCATGGCGGGCTTGACCTTGAACCCGGCCGGGATCAGACACCCGCAGAACCTGCGGATTTTGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References