185536

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4580513..4580879 Replicon chromosome
Accession NZ_CP066986
Organism Xanthomonas campestris pv. campestris strain 15-1

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH296_RS20060 Protein ID WP_011270059.1
Coordinates 4580513..4580647 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH296_RS20065 Protein ID WP_011038999.1
Coordinates 4580727..4580879 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH296_RS20040 (JH296_19990) 4575776..4577428 - 1653 WP_043890286.1 M28 family metallopeptidase -
JH296_RS20045 (JH296_19995) 4577593..4578537 - 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH296_RS20050 (JH296_20000) 4578621..4579910 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH296_RS20055 (JH296_20005) 4580070..4580279 - 210 WP_011038998.1 CsbD family protein -
JH296_RS20060 (JH296_20010) 4580513..4580647 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH296_RS20065 (JH296_20015) 4580727..4580879 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH296_RS20070 (JH296_20020) 4580990..4581913 - 924 WP_040942405.1 arginase -
JH296_RS20075 (JH296_20025) 4582227..4582688 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH296_RS20080 (JH296_20030) 4582771..4583130 + 360 WP_011039002.1 hypothetical protein -
JH296_RS20085 (JH296_20035) 4583233..4584150 + 918 WP_274496807.1 hypothetical protein -
JH296_RS20090 (JH296_20040) 4584147..4584689 + 543 WP_012439507.1 GTPase -
JH296_RS20095 (JH296_20045) 4585023..4585706 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185536 WP_011270059.1 NZ_CP066986:c4580647-4580513 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185536 NZ_CP088292:c353821-353510 [Phyllobacterium sp. T1018]
ATGATAGGACTGAAACAGACCTCCGTTTATCGTAAGTGGGAAAGCAAGCTGAAAGACCAGAGGGCGAGGGCGGTCATCGC
TGCCCGCCTCTTCCGCTTGGCCAGTGGGCTTGGGAGCGACATTGCATTTGTAGGTGGTGGCGTAAGCGAACTGAGAATTC
ACTATGGACCGGGATACCGGGTTTATTTCCGGCGTCACGGCGAACAGATTGTCATCCTTCTTTGTGGCGGTGACAAGCAG
ACGCAAGATCGGGACATCCGCGAGGCTCGGCGATTGGCAATAGATTGGAGGGATGATGACGAAGCTCTATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185536 WP_011038999.1 NZ_CP066986:c4580879-4580727 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185536 NZ_CP088292:c353529-353242 [Phyllobacterium sp. T1018]
ATGATGACGAAGCTCTATGACTACAATCCTGCCGACGCACTCAAATCTGACGAGGCAATAGAGTTATTTCTTGCCGACGC
ATTTGAAACTGGCGATTCTGCCTACATTGCGAAGGCCATCGGGGTAGTCGCAAGATCGAAGGGCATGGCAACGATCGCAC
GCGAGACTGGATTGTCCCGGGAACAACTTTACCGCTCACTGAGTGAAAGTGGAAACCCTACACTGGCCACAACGATAGCC
GTGTTGAAGGCAGTCGGCTTTCAACTGAGTGGCAAACGGGCGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References