185533

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 353179..353545 Replicon chromosome
Accession NZ_CP066985
Organism Xanthomonas campestris pv. campestris strain 25-4

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH294_RS01470 Protein ID WP_011270059.1
Coordinates 353411..353545 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH294_RS01465 Protein ID WP_011038999.1
Coordinates 353179..353331 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH294_RS01435 (JH294_01420) 348352..349035 - 684 WP_011039005.1 dTMP kinase -
JH294_RS01440 (JH294_01425) 349369..349911 - 543 WP_012439507.1 GTPase -
JH294_RS01445 (JH294_01430) 349908..350825 - 918 WP_274496807.1 hypothetical protein -
JH294_RS01450 (JH294_01435) 350928..351287 - 360 WP_011039002.1 hypothetical protein -
JH294_RS01455 (JH294_01440) 351370..351831 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH294_RS01460 (JH294_01445) 352145..353068 + 924 WP_040942405.1 arginase -
JH294_RS01465 (JH294_01450) 353179..353331 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH294_RS01470 (JH294_01455) 353411..353545 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH294_RS01475 (JH294_01460) 353779..353988 + 210 WP_011038998.1 CsbD family protein -
JH294_RS01480 (JH294_01465) 354148..355437 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH294_RS01485 (JH294_01470) 355521..356465 + 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH294_RS01490 (JH294_01475) 356630..358282 + 1653 WP_043890286.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185533 WP_011270059.1 NZ_CP066985:353411-353545 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185533 NZ_CP088290:86867-87253 [Bradyrhizobium septentrionale]
ATGGTGATCGACTCATCCGCAATTCTGGCGATTTTTTTGAATGAGCCGGAAGCCAGCGAATTCGAGCATCGCATTGCGGC
CGATCCTGTCCGGTTGATTTCGGCGGCGACGGTGTTGGAAACTGGAATAGGGATCGAGTCAAAGTTGGGCGATGGGGGCA
GCGCCGAGCTTGATCTCTGGCTACACAAGGTTGGTGTCGAGATTGTTCCGGTCACGGCCGGGCATGCGGATCAGGCACGG
CGGGCGTGGCGGCGGTATGGGAAAGGCCGGCATCCCGCCAAGCTGAACTTTGGCGATTGCTTTTCTTACGCTCTCGCTGC
CCTCACCGGGGAACCCCTGCTGTTCAAGGGCAGCGACTTCTCGCAGACCGACATCAAGGCGGCCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185533 WP_011038999.1 NZ_CP066985:353179-353331 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185533 NZ_CP088290:86613-86867 [Bradyrhizobium septentrionale]
ATGGCGCTGAGCATCAAGGATCCCGAAACCGAAAAACTCGCGCGCACGCTAGCAGAGCGGACAGGGGAAACCATCACCGT
CGCGACCCGGCGCGCGATCGAGGATAGGTTGCGACGGGTCGGGGCCGACGCGACCAAGGCCACGCTGATTGAGGACATGG
AAGCCATTCGGCGCCGCCTCGCTACCCTCCCCGTCCTCGATCCACGCAGCATGGATGACATCCTCGGGTACGACGAAAAC
GGCTTGCCGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References