Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 154439..154805 Replicon chromosome
Accession NZ_CP066984
Organism Xanthomonas campestris pv. campestris strain 27-10

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH284_RS00670 Protein ID WP_011270059.1
Coordinates 154671..154805 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH284_RS00665 Protein ID WP_011038999.1
Coordinates 154439..154591 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH284_RS00635 (JH284_00630) 149612..150295 - 684 WP_011039005.1 dTMP kinase -
JH284_RS00640 (JH284_00635) 150629..151171 - 543 WP_012439507.1 GTPase -
JH284_RS00645 (JH284_00640) 151168..152085 - 918 WP_274496807.1 hypothetical protein -
JH284_RS00650 (JH284_00645) 152188..152547 - 360 WP_011039002.1 hypothetical protein -
JH284_RS00655 (JH284_00650) 152630..153091 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH284_RS00660 (JH284_00655) 153405..154328 + 924 WP_040942405.1 arginase -
JH284_RS00665 (JH284_00660) 154439..154591 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH284_RS00670 (JH284_00665) 154671..154805 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH284_RS00675 (JH284_00670) 155039..155248 + 210 WP_011038998.1 CsbD family protein -
JH284_RS00680 (JH284_00675) 155408..156697 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH284_RS00685 (JH284_00680) 156781..157725 + 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH284_RS00690 (JH284_00685) 157890..159542 + 1653 WP_043890286.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185531 WP_011270059.1 NZ_CP066984:154671-154805 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185531 NZ_CP088290:86094-86501 [Bradyrhizobium septentrionale]
ATGTATCTAATTGATACCAATGTTGTTTCCGAGGCTCGGCGCGGCTCCCCGCAGGCAACCGGCTGGCTGCGCTCTGTAGA
TCCGGCGAGCGTCCACCTGAGCACCCTCACTCTTGGCGAGATTATGCGCGGCATTGCGCTGAAGCAGAAGTCGGATCCCA
AGGCGGCCGGCCATCTTGCCGAATGGCTGCGCAAGCTGCGCCACGACCATGCCGACCGCATCCTGGCGGTGACCGACCAG
ATCTCCGTCGAGTGGGGTCGCATCGCCGCGATCCGACCGCACGGCGATATCGACGGACTGATCGCCGCAACCGCGATCGT
CCACGACCTCATTATCGTCACCCGCAATGTGGGGGATTTCGAGGATACGGGCGCAACGGTGATCAATCCCTGGGAGACAT
CGGCATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185531 WP_011038999.1 NZ_CP066984:154439-154591 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185531 NZ_CP088290:85840-86094 [Bradyrhizobium septentrionale]
ATGGAATGGCCTCTGCAGGACGCCAAGAACCAGTTCTCCAAGGTGGTGCAGAAGGCCCGCCTCGAAGGCCCGCAGGTCGT
CACGCTGCGCGGGATGCGCGCCGCGGTGGTGCTGTCGGCCGCCGATTACGATGCGCTGCGTTCCGGGCGGCCGACTTTGG
TCGACGACTTGCTGGCCGGGCCAAGCTGGGATGACGAACTGGTCGAGGCAGTAGCGCAGCGCGCCGAGACCCCCAGCCGC
GACGCGGCTTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References