185529

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 353235..353601 Replicon chromosome
Accession NZ_CP066983
Organism Xanthomonas campestris pv. campestris strain 27-6

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH258_RS01470 Protein ID WP_011270059.1
Coordinates 353467..353601 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH258_RS01465 Protein ID WP_011038999.1
Coordinates 353235..353387 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH258_RS01435 (JH258_01420) 348408..349091 - 684 WP_011039005.1 dTMP kinase -
JH258_RS01440 (JH258_01425) 349425..349967 - 543 WP_012439507.1 GTPase -
JH258_RS01445 (JH258_01430) 349964..350881 - 918 WP_274496807.1 hypothetical protein -
JH258_RS01450 (JH258_01435) 350984..351343 - 360 WP_011039002.1 hypothetical protein -
JH258_RS01455 (JH258_01440) 351426..351887 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH258_RS01460 (JH258_01445) 352201..353124 + 924 WP_040942405.1 arginase -
JH258_RS01465 (JH258_01450) 353235..353387 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH258_RS01470 (JH258_01455) 353467..353601 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH258_RS01475 (JH258_01460) 353835..354044 + 210 WP_011038998.1 CsbD family protein -
JH258_RS01480 (JH258_01465) 354204..355493 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH258_RS01485 (JH258_01470) 355577..356521 + 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH258_RS01490 (JH258_01475) 356686..358338 + 1653 WP_043890286.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185529 WP_011270059.1 NZ_CP066983:353467-353601 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185529 NZ_CP088288:8028535-8028735 [Bradyrhizobium septentrionale]
ATTAATACACACACGAGGTCAGCAGATGTCATCAGGGTCCTGAAGGACGATGGGTGGAAGCCGGTGGCCCAGAAGGGCAG
CCACATCCAGTTCAAGCACCCGACAAAGAGCGGCCGCGTGACGGTACCGCATCCGAAGCGTGACATCCCTATCGGCACTT
TGAGGAGCATCGAAAAGCAAGCCGACCTGAAACTAAGATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185529 WP_011038999.1 NZ_CP066983:353235-353387 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185529 NZ_CP088288:8028784-8029176 [Bradyrhizobium septentrionale]
ATGCGACACTACATTGCACTGATCCATAAGGATGCAGACAGCGACTACGGCGTGTCATTTCCGGATCTTCCTGGCGTTGT
AACTGCTGGAACGAATTTAGATGATGCGCGCGCCATGGCAACGGAAGCTCTGGCTCTTCATCTAGAGGGTATGGTTGAAG
ACGGCGAAGCCGTCCCAGAACCCTCCTCCCTTGAGGAGATCATGGCAGATGCCGAGAACAGAGACGGCGTTGCCGTTCTA
ATTCCTGTACCAGCGACGGAAGTGAAGACGGTACGCGTCAACGTCACTCTTCCCGCCGATGTCTTGAACGAGATTGACCA
CTACGCTGAACAGCATGGTTTCACGCGTTCTGGTTTTCTCGTTCAAGCCGCAAAGAAAGCGATCGCGGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References