185527

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 353234..353600 Replicon chromosome
Accession NZ_CP066982
Organism Xanthomonas campestris pv. campestris strain 27-9

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH271_RS01460 Protein ID WP_011270059.1
Coordinates 353466..353600 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH271_RS01455 Protein ID WP_011038999.1
Coordinates 353234..353386 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH271_RS01425 (JH271_01415) 348407..349090 - 684 WP_011039005.1 dTMP kinase -
JH271_RS01430 (JH271_01420) 349424..349966 - 543 WP_012439507.1 GTPase -
JH271_RS01435 (JH271_01425) 349963..350880 - 918 WP_274496807.1 hypothetical protein -
JH271_RS01440 (JH271_01430) 350983..351342 - 360 WP_011039002.1 hypothetical protein -
JH271_RS01445 (JH271_01435) 351425..351886 - 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH271_RS01450 (JH271_01440) 352200..353123 + 924 WP_040942405.1 arginase -
JH271_RS01455 (JH271_01445) 353234..353386 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH271_RS01460 (JH271_01450) 353466..353600 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH271_RS01465 (JH271_01455) 353834..354043 + 210 WP_011038998.1 CsbD family protein -
JH271_RS01470 (JH271_01460) 354203..355492 + 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH271_RS01475 (JH271_01465) 355576..356520 + 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH271_RS01480 (JH271_01470) 356685..358337 + 1653 WP_043890286.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185527 WP_011270059.1 NZ_CP066982:353466-353600 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185527 NZ_CP088285:8465484-8465672 [Bradyrhizobium septentrionale]
ATGAGGTCAGCAGATGTCATCAGGGTCCTGAAGGACGATGGGTGGAAGCCGGTGGCCCAGAAGGGCAGCCACATCCAGTT
CAAGCACCCGACAAAGAGCGGCCGCGTGACGGTACCGCATCCGAAGCGTGACATCCCTATCGGCACTTTGAGGAGCATCG
AAAAGCAAGCCGACCTGAAACTAAGATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185527 WP_011038999.1 NZ_CP066982:353234-353386 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185527 NZ_CP088285:8465721-8466113 [Bradyrhizobium septentrionale]
ATGCGACACTACATTGCACTGATCCATAAGGATGCAGACAGCGACTACGGCGTGTCATTTCCGGATCTTCCTGGCGTTGT
AACTGCTGGAACGAATTTAGATGATGCGCGCGCCATGGCAACGGAAGCTCTGGCTCTTCATCTAGAGGGTATGGTTGAAG
ACGGCGAAGCCGTCCCAGAACCCTCCTCCCTTGAGGAGATCATGGCAGATGCCGAGAACAGGGACGGCGTTGCCGTTCTA
ATTCCTGTACCAGCGACGGAAGTGAAGACGGTACGCGTCAACGTCACTCTTCCCGCCGATGTCTTGAACGAGATTGACCA
CTACGCTGAACAGCATGGTTTCACGCGTTCTGGTTTTCTCGTTCAAGCCGCAAAGAAAGCGATCGCGGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References