Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4577909..4578275 Replicon chromosome
Accession NZ_CP066981
Organism Xanthomonas campestris pv. campestris strain 28-1

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH301_RS20050 Protein ID WP_011270059.1
Coordinates 4577909..4578043 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH301_RS20055 Protein ID WP_011038999.1
Coordinates 4578123..4578275 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH301_RS20030 (JH301_19955) 4573172..4574824 - 1653 WP_043890286.1 M28 family metallopeptidase -
JH301_RS20035 (JH301_19960) 4574989..4575933 - 945 WP_043890287.1 MBL fold metallo-hydrolase -
JH301_RS20040 (JH301_19965) 4576017..4577306 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH301_RS20045 (JH301_19970) 4577466..4577675 - 210 WP_011038998.1 CsbD family protein -
JH301_RS20050 (JH301_19975) 4577909..4578043 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH301_RS20055 (JH301_19980) 4578123..4578275 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH301_RS20060 (JH301_19985) 4578386..4579309 - 924 WP_040942405.1 arginase -
JH301_RS20065 (JH301_19990) 4579623..4580084 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH301_RS20070 (JH301_19995) 4580167..4580526 + 360 WP_011039002.1 hypothetical protein -
JH301_RS20075 (JH301_20000) 4580629..4581546 + 918 WP_274496807.1 hypothetical protein -
JH301_RS20080 (JH301_20005) 4581543..4582085 + 543 WP_012439507.1 GTPase -
JH301_RS20085 (JH301_20010) 4582419..4583102 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185526 WP_011270059.1 NZ_CP066981:c4578043-4577909 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185526 NZ_CP088285:2106348-2106644 [Bradyrhizobium septentrionale]
TTGAAACTCGTCTGGTCGCGCTTCGCGTTGTCCGATCGCGACGACATTTTCAGCTACATCGAAGCCGAGAATCCCCGCGC
TGCGGTTCATGTCGACGAACAGATCGCCGACGCCGCGCGGCGCCTGCTCGACTTTCCTGACAGTGGCCGGCCCGGGCGTG
TCGCCGGCACGCGCGAGTTGGTCATCCCGCGCACACCTTATATCGCGGCGTACCTGGTCGACGGCGAGACTGGCCGCATC
TTGCGCGTGCTTCACGGCGCGCAGATGTGGCCCGACGAACTTACAAATGACGATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185526 WP_011038999.1 NZ_CP066981:c4578275-4578123 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185526 NZ_CP088285:2106043-2106351 [Bradyrhizobium septentrionale]
ATGGCTTCGAATGCCCTAGTCCAAACCCGCATCGATGCGGACGTAAAGGAAAAGGCCACCGCGGTTCTGGAAAACATGGG
TCTCACGGTATCCGACGCCGTGCGGATCCTGCTGACACGCACGGCCAACGAGGGGGCGCTTCCACTGGAGCTCGTGAGCA
ACAGCCAAGCTTACGACAGCTGGTTTGGTGAGAAGGTGCGCCATGCGCTGGCGGATACCCGGCCCAATCTCGATGATTCC
GAGGTCGAAGCGCATTTCGCGCAACGCCGCACCGCTGCGCTTCGAAAAGCGGCGGAGCGTAAACGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References