Detailed information of TA system TA185524

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4716062..4716428
• Replicon: chromosome
• Accession: NZ_CP066980
• Organism: Xanthomonas campestris pv. campestris strain 55-1

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: G0CKD4
• Locus tag: JH267_RS20585
• Protein ID: WP_011270059.1
• Coordinates: 4716062..4716196 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: JH267_RS20590
• Protein ID: WP_267314524.1
• Coordinates: 4716276..4716428 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JH267_RS20565 (JH267_20560)	4711325..4712977	-	1653	WP_267315112.1	M28 family metallopeptidase	-
JH267_RS20570 (JH267_20565)	4713142..4714086	-	945	WP_267314523.1	MBL fold metallo-hydrolase	-
JH267_RS20575 (JH267_20570)	4714170..4715459	-	1290	WP_029217012.1	tryptophan--tRNA ligase	-
JH267_RS20580 (JH267_20575)	4715619..4715828	-	210	WP_011038998.1	CsbD family protein	-
JH267_RS20585 (JH267_20580)	4716062..4716196	-	135	WP_011270059.1	entericidin A/B family lipoprotein	Toxin
JH267_RS20590 (JH267_20585)	4716276..4716428	-	153	WP_267314524.1	entericidin A/B family lipoprotein	Antitoxin
JH267_RS20595 (JH267_20590)	4716539..4717462	-	924	WP_040942405.1	arginase	-
JH267_RS20600 (JH267_20595)	4717776..4718237	+	462	WP_228422658.1	roadblock/LC7 domain-containing protein	-
JH267_RS20605 (JH267_20600)	4718320..4718679	+	360	WP_011039002.1	hypothetical protein	-
JH267_RS20610 (JH267_20605)	4718782..4719699	+	918	WP_267314525.1	hypothetical protein	-
JH267_RS20615 (JH267_20610)	4719696..4720238	+	543	WP_012439507.1	GTPase	-
JH267_RS20620 (JH267_20615)	4720573..4721256	+	684	WP_011039005.1	dTMP kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4431.27 Da
• Isoelectric Point: 9.3487

>T185524 WP_011270059.1 NZ_CP066980:c4716196-4716062 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Nucleotide

• Length: 135 bp

>T185524 NZ_CP088282:2498662-2498958 [Bradyrhizobium quebecense]
ATGATCCTGAGCTTCCGGGACGAATGGCTGCGCGCTTTCTTCACGGAGGACGCGAAATCGCGAAACATCCCGTCGGATCT
TGAAGACCGTCTGTTTCGCAAGCTGCAGATGCTCGATGATGCGACGACTGATCAGGACCTGCGGGTGCCGCCGAGCAATC
ATTTTGAGAAACTCCGAGGCAATCTTGCGGGGCTTCATTCCATTCGCGTCAACAAGCAATGGCGCCTTGTCTTTCGGTGG
TCGGGCGCGCGAGGCGAAACACAAGGCGTCTACCTCGGCGACCACAGTTACAGATGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5172.16 Da
• Isoelectric Point: 8.7942

>AT185524 WP_267314524.1 NZ_CP066980:c4716428-4716276 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGNKVEKTADKCSDGKC

Nucleotide

• Length: 153 bp

>AT185524 NZ_CP088282:2498974-2499282 [Bradyrhizobium quebecense]
ATGCTGACGACCAAGCGCAAGCCCGCCACGTTGGGCGAGATTCTCAGGGAAGAATTCATGGCACCGTTGGGGCTGACCCA
AGGCGCCTTGGCCGAGGCCATGGGAGTTCAGCGCAAGCATGTCAATGAATTGTGCAATGATCGCCGGAACGTCACCGCGG
CAACCGCGCTGATTCTTGCCCGCGTATTCGGCAACAGCCCGGAGTTCTGGCTGAACGTCCAGCGACGCACTGACCTTTGG
CAAGCCATGAACTCGCCGAGCGAGCGGAAGCGCATCGAACGCGCGAAGCCGCTTGGAAGAGCCGCTTGA

Structures

Toxin

• AlphaFold DB: A0A0H2XDQ0