185519

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 426266..426629 Replicon chromosome
Accession NZ_CP066978
Organism Xanthomonas campestris pv. incanae strain 18048

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH290_RS01775 Protein ID WP_011270059.1
Coordinates 426495..426629 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH290_RS01770 Protein ID WP_011038999.1
Coordinates 426266..426418 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH290_RS01740 (JH290_01740) 421444..422121 - 678 WP_223647312.1 dTMP kinase -
JH290_RS01745 (JH290_01745) 422456..422998 - 543 WP_076035808.1 GTPase -
JH290_RS01750 (JH290_01750) 422995..423912 - 918 WP_223647313.1 hypothetical protein -
JH290_RS01755 (JH290_01755) 424015..424374 - 360 WP_011039002.1 hypothetical protein -
JH290_RS01760 (JH290_01760) 424457..424918 - 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH290_RS01765 (JH290_01765) 425232..426155 + 924 WP_057673597.1 arginase -
JH290_RS01770 (JH290_01770) 426266..426418 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH290_RS01775 (JH290_01775) 426495..426629 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH290_RS01780 (JH290_01780) 426862..427071 + 210 WP_011038998.1 CsbD family protein -
JH290_RS01785 (JH290_01785) 427231..428520 + 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH290_RS01790 (JH290_01790) 428604..429548 + 945 WP_223647314.1 MBL fold metallo-hydrolase -
JH290_RS01795 (JH290_01795) 429713..431365 + 1653 WP_181921563.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185519 WP_011270059.1 NZ_CP066978:426495-426629 [Xanthomonas campestris pv. incanae]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185519 NZ_CP088280:7590860-7591285 [Bradyrhizobium barranii subsp. barranii]
GTGAACCTGCTCCTCGACACCAACGTGCTGTCGGAGGTTCAGCGGCCGGCGCCTTCCCCGAAAGTCCTGGCATGGCTCGA
TACGGTCGATGAGGATCGCGCGTTCATCAGCGTTGCCTCGATCGCCGAGCTTCGCCGCGGTATCGCCCTGCTGGATGACG
GCCGTCGGCGCGCCGCGCTGGCCGCTTGGCTCGCCCACGACCTGCCGGCTCGGTTCGCGCAGCGCATCCTGCCGATCGAC
CACGCGGTCGCCGAGCGCTGGGGCGACCTGATGGCGCAGAGCCGTCGCAATGGCGTCGCGTTGTCCGTGATGGACGGCTT
CTTTGCGGCCACCGCGCTCGCCAACGATCTCACGCTCGTCACACGCAATGTGAAAGATTTTGCGGCCTTCGGCGTTCCGC
TGCTCGACCCATGGAGCGACGCCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185519 WP_011038999.1 NZ_CP066978:426266-426418 [Xanthomonas campestris pv. incanae]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185519 NZ_CP088280:7590582-7590863 [Bradyrhizobium barranii subsp. barranii]
ATGACAGACCGCAGCACCGCCCCCGATTCGCCCCCGACTGACACGTGGACGCTCGCCAATGCCAAGGCACGCCTGTCCGA
GGTGGTCGATCGCGCCCAAACTGGCCCCCAGATCATCACCCGACACGGCAGGCCCAATGCCGTGGTCGTTTCCGCGGATG
AATGGGCGCGAAAGACGGCGCGCAAAGGCACGCTGGCCGAATTCCTGCTGGCGTCGCCGCTGCGCGGTGCCGACCTCGAA
CTTGAACGGGTGCAGGATGAACCGCGCGACGAGATGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References