Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4940614..4941020 Replicon chromosome
Accession NZ_CP066975
Organism Xanthomonas campestris pv. campestris strain 10006

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH265_RS21430 Protein ID WP_267129426.1
Coordinates 4940865..4941020 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH265_RS21425 Protein ID WP_070697976.1
Coordinates 4940614..4940868 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH265_RS21400 (JH265_21400) 4936113..4936952 + 840 WP_014509612.1 SDR family oxidoreductase -
JH265_RS21405 (JH265_21405) 4937096..4938361 + 1266 WP_043877851.1 phospholipase D-like domain-containing protein -
JH265_RS21410 (JH265_21410) 4938379..4938908 - 530 Protein_4135 hypothetical protein -
JH265_RS21415 (JH265_21415) 4939167..4939373 + 207 WP_014509615.1 hypothetical protein -
JH265_RS21420 (JH265_21420) 4939360..4940475 + 1116 WP_050912541.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH265_RS21425 (JH265_21425) 4940614..4940868 + 255 WP_070697976.1 Arc family DNA-binding protein Antitoxin
JH265_RS21430 (JH265_21430) 4940865..4941020 + 156 WP_267129426.1 hypothetical protein Toxin
JH265_RS21435 (JH265_21435) 4941065..4942432 - 1368 WP_011035783.1 IS5-like element IS1478 family transposase -
JH265_RS21440 (JH265_21440) 4942692..4943549 - 858 WP_274503024.1 SIR2 family protein -
JH265_RS21445 (JH265_21445) 4943551..4944570 - 1020 WP_011039254.1 AAA family ATPase -
JH265_RS21450 (JH265_21450) 4944753..4944905 - 153 Protein_4143 topoisomerase DNA-binding C4 zinc finger domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185518 WP_267129426.1 NZ_CP066975:4940865-4941020 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185518 NZ_CP088280:2922767-2922991 [Bradyrhizobium barranii subsp. barranii]
ATCGATTGGGAAATGCTTCAGCGGCGGGATTTCAAAAATGATCCCGAAGATCCGTCGAAGAAAGAGCGATATCAGGCAGA
AGCTCTTGTTCATAAGCACATGCCGATGGCATCGCTCTTCGGGTTCGCTTGCTACAATGATGCTTGCGTCCAGACGATAC
AAAATGCTCTGGCAAGTCGAAAAATGACAGCCGACGTAGTCAATAAATCAGACTGGTATTTCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9056.45 Da        Isoelectric Point: 10.4748

>AT185518 WP_070697976.1 NZ_CP066975:4940614-4940868 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAARPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185518 NZ_CP088280:2922991-2924052 [Bradyrhizobium barranii subsp. barranii]
ATGATCGAATTCACGCGCGGGAATCTTCTCGATGCCAAGGTTGATGCGCTTGTAAACACCGTTAACACAGTCGGTGTAAT
GGGTAAGGGCGTGGCGTTGATGTTCAAGGAGGCGTTTCCGGAAAACTTCAAGGACTATGAGGCTGCGTGCAAGAAGAAGG
CCGTGAAAGTCGGCAAAATGTTCGTGACTAAGCGACTACTTAGTCCGAAGTGGATTATAAATTTCCCAACCAAAGAACAC
TGGCGTGGCGATTCCAAGTTGGAGTGGATCGAAACGGGTTTGGAGGACTTGAAGCGTGTAATCATTGAGAATGGTATTGA
ATCGATCGCCATCCCGCCGTTGGGAAGTGGAAACGGTGGCTTAAAGTGGGAAGATGTGCGCCCAAAGATTGAAGCGGCCC
TTAGCTCGTTGAAGGACGTTACTGTATTCGTATACGAGCCGACTGATCAGTATCAAAACGTCGCAAAGCGGTCCGGAGTC
GAGCAGCTAACTCCCGCGCGTGCTCTAGTGGCGGAGCTAGTTCGACGATATTGGATATTGGGCATTGAGTGCTCGCTTCT
TGAAATTCAGAAGCTTGCCTACTTCTTAGAGCGCAGTATTGAAATTCTTAAAGTCAAAAACCCCCTTGATCTTCGGTTTC
AAGCGGACAAGTACGGTCCTTATGCGCCTCGCTTGACGCATCTTTTAGACGGACTTGACGGCAGCTATTTGCATTGCGGC
AAGCGAATTGGCGATGCCAGTCCGTTCGATGTCATTTGGTTCGAAGATTCGAAGCGAGATAAGGTTGCCGCCTACCTTCG
ATCAGGGGAGGCGAAGGCCTATCTGCCTGCTTTGGAGAATACTGCCAAATTGATAGACGGCTTTGAATCGCCCCTTGGTG
TGGAGCTTTTGGCGACCGTGGATTGGTTGGTTCACAAGGACGGCATTAAGTTGGAACGTGAAGCAGTGAAGGTCGCTCTG
AAAACATGGACCGGTGGAGAAAAATCTTCTGAAAGAAAACTTAAACTCTTTGAAGATCGGCTGATTGATCTGGCGCTTGA
ACGACTGCATTCGTTCGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References