185517

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4607585..4607948 Replicon chromosome
Accession NZ_CP066975
Organism Xanthomonas campestris pv. campestris strain 10006

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH265_RS20060 Protein ID WP_011270059.1
Coordinates 4607585..4607719 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH265_RS20065 Protein ID WP_011038999.1
Coordinates 4607796..4607948 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH265_RS20040 (JH265_20055) 4602849..4604501 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH265_RS20045 (JH265_20060) 4604666..4605610 - 945 WP_043877842.1 MBL fold metallo-hydrolase -
JH265_RS20050 (JH265_20065) 4605694..4606983 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH265_RS20055 (JH265_20070) 4607143..4607352 - 210 WP_011038998.1 CsbD family protein -
JH265_RS20060 (JH265_20075) 4607585..4607719 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH265_RS20065 (JH265_20080) 4607796..4607948 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH265_RS20070 (JH265_20085) 4608059..4608989 - 931 Protein_3878 arginase -
JH265_RS20075 (JH265_20090) 4609303..4609764 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH265_RS20080 (JH265_20095) 4609847..4610206 + 360 WP_011039002.1 hypothetical protein -
JH265_RS20085 (JH265_20100) 4610309..4611226 + 918 WP_012439506.1 hypothetical protein -
JH265_RS20090 (JH265_20105) 4611223..4611765 + 543 WP_011039004.1 GTPase -
JH265_RS20095 (JH265_20110) 4612100..4612783 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185517 WP_011270059.1 NZ_CP066975:c4607719-4607585 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185517 NZ_CP088279:68587-68994 [Bradyrhizobium barranii subsp. barranii]
ATGTATCTCATTGATACCAACGTCGTTTCCGAGGCTCGGCGCGGCTCCCCGCAGGCAACCGGCTGGCTGCGCTCGGTAGA
TCCGGCGAGCGTCCACCTGAGCACCCTCACCCTCGGCGAGATCATGCGCGGCATCGCGCTGAAGCAGAAATCGGACCCGA
AGGCGGCCGGCCATCTGGCCGAATGGTTGCGCAAGCTGCGCCACGACCACGCCGACCGCATCTTGGCGGTGACCGACCAG
ATCTCCGTCGAGTGGGGTCGCATCGCCGCGATCCGACCACGCGGCGATATCGACGGGCTGATCGCCGCAACCGCGATCGT
CCACGACCTCATCCTCGTCACCCGCAATGTGGGGGATTTCGACGATACGGGCGCAACGGTGATCAATCCCTGGGAGGCGT
CGACATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185517 WP_011038999.1 NZ_CP066975:c4607948-4607796 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185517 NZ_CP088279:68333-68587 [Bradyrhizobium barranii subsp. barranii]
ATGGAATGGCCGCTGCAGGACGCCAAGAACCAGTTTTCCAAGGTGGTGCAGAAGGCCCGCCTGGAAGGCCCGCAGGTCGT
CACCCTGCGCGGGATGCGCGCCGCGGTGGTGCTGTCGGCCGCCGATTACGATGCGCTGCGCTCCGGGCGGCCGACCTTGG
TCGACGACTTGCTGGCCGGGCCAAGCTGGGATGACGAACTGGCCGAAGAAGCGATGCGGCGCATCAAGACCCCCAGCCGC
GACGCGGCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References