185515

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 4940647..4941053 Replicon chromosome
Accession NZ_CP066972
Organism Xanthomonas campestris pv. campestris strain 10008

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH312_RS21430 Protein ID WP_267129426.1
Coordinates 4940898..4941053 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH312_RS21425 Protein ID WP_070697976.1
Coordinates 4940647..4940901 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH312_RS21400 (JH312_21405) 4936146..4936985 + 840 WP_014509612.1 SDR family oxidoreductase -
JH312_RS21405 (JH312_21410) 4937129..4938394 + 1266 WP_043877851.1 phospholipase D-like domain-containing protein -
JH312_RS21410 (JH312_21415) 4938412..4938941 - 530 Protein_4135 hypothetical protein -
JH312_RS21415 (JH312_21420) 4939200..4939406 + 207 WP_014509615.1 hypothetical protein -
JH312_RS21420 (JH312_21425) 4939393..4940508 + 1116 WP_050912541.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH312_RS21425 (JH312_21430) 4940647..4940901 + 255 WP_070697976.1 Arc family DNA-binding protein Antitoxin
JH312_RS21430 (JH312_21435) 4940898..4941053 + 156 WP_267129426.1 hypothetical protein Toxin
JH312_RS21435 (JH312_21440) 4941098..4942465 - 1368 WP_011035783.1 IS5-like element IS1478 family transposase -
JH312_RS21440 (JH312_21445) 4942725..4943582 - 858 WP_274503024.1 SIR2 family protein -
JH312_RS21445 (JH312_21450) 4943584..4944603 - 1020 WP_011039254.1 AAA family ATPase -
JH312_RS21450 (JH312_21455) 4944786..4944938 - 153 Protein_4143 topoisomerase DNA-binding C4 zinc finger domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185515 WP_267129426.1 NZ_CP066972:4940898-4941053 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185515 NZ_CP088273:3267299-3267586 [Phyllobacterium sp. T1293]
ATGGCAACGAAGCTATATGACTACGATCCTGCTGATGCTTTGAAATCGGATGACGCAATCGAGGTGTTTCTGGCTGATGC
ATTCGAAACGGGTGATGCCGGTTATATTGCCAAGGCTTTGGGTCTTGTCGCTCGCGCGAAAGGCATGACCAAAATTGCGC
GGCAAACGGGTTTGGCGCGTGAGCAACTCTATCGTTCGTTAAGTGAAAACGGAAACCCGACGCTTGAAACAACAATAGCG
GTTATGAAGGCAGTGGGATTTCAGATCACCGGAAAACGCGCTGCATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9056.45 Da        Isoelectric Point: 10.4748

>AT185515 WP_070697976.1 NZ_CP066972:4940647-4940901 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAARPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185515 NZ_CP088273:3266968-3267318 [Phyllobacterium sp. T1293]
ATATGGACATTTCGTAATTTAAAAAATACAGTTTTAACGCGGATCAAGCAGACTGATACCTATCGGATATGGGAACGAAA
ACTTAGGGACGATAGTGCGAAGGCAGCGATTGCTGCCCGCTTGTTTCGCTTGGCCAATGGTTTGATCGGTGACGTTTCAT
CGGTTGGCGAGGGCGTCCACGAATTGCGGGTTCATTATGGTCCCGGTTACCGGATTTATTTCAAACAATGCAGCACGGAG
CTTGTGATTTTATTGTGCGGTGGAAACAAGCGTACGCAGCAGCGGGACATAGGCAAAGCGAAACTGCTGGCTGCGGAATG
GAAAAATGACAATGGCAACGAAGCTATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References