Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4607618..4607981 Replicon chromosome
Accession NZ_CP066972
Organism Xanthomonas campestris pv. campestris strain 10008

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH312_RS20060 Protein ID WP_011270059.1
Coordinates 4607618..4607752 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH312_RS20065 Protein ID WP_011038999.1
Coordinates 4607829..4607981 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH312_RS20040 (JH312_20055) 4602882..4604534 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH312_RS20045 (JH312_20060) 4604699..4605643 - 945 WP_043877842.1 MBL fold metallo-hydrolase -
JH312_RS20050 (JH312_20065) 4605727..4607016 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH312_RS20055 (JH312_20070) 4607176..4607385 - 210 WP_011038998.1 CsbD family protein -
JH312_RS20060 (JH312_20075) 4607618..4607752 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH312_RS20065 (JH312_20080) 4607829..4607981 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH312_RS20070 (JH312_20085) 4608092..4609022 - 931 Protein_3878 arginase -
JH312_RS20075 (JH312_20090) 4609336..4609797 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH312_RS20080 (JH312_20095) 4609880..4610239 + 360 WP_011039002.1 hypothetical protein -
JH312_RS20085 (JH312_20100) 4610342..4611259 + 918 WP_012439506.1 hypothetical protein -
JH312_RS20090 (JH312_20105) 4611256..4611798 + 543 WP_011039004.1 GTPase -
JH312_RS20095 (JH312_20110) 4612133..4612816 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185514 WP_011270059.1 NZ_CP066972:c4607752-4607618 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185514 NZ_CP088273:3266968-3267318 [Phyllobacterium sp. T1293]
ATATGGACATTTCGTAATTTAAAAAATACAGTTTTAACGCGGATCAAGCAGACTGATACCTATCGGATATGGGAACGAAA
ACTTAGGGACGATAGTGCGAAGGCAGCGATTGCTGCCCGCTTGTTTCGCTTGGCCAATGGTTTGATCGGTGACGTTTCAT
CGGTTGGCGAGGGCGTCCACGAATTGCGGGTTCATTATGGTCCCGGTTACCGGATTTATTTCAAACAATGCAGCACGGAG
CTTGTGATTTTATTGTGCGGTGGAAACAAGCGTACGCAGCAGCGGGACATAGGCAAAGCGAAACTGCTGGCTGCGGAATG
GAAAAATGACAATGGCAACGAAGCTATATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185514 WP_011038999.1 NZ_CP066972:c4607981-4607829 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185514 NZ_CP088273:3267299-3267586 [Phyllobacterium sp. T1293]
ATGGCAACGAAGCTATATGACTACGATCCTGCTGATGCTTTGAAATCGGATGACGCAATCGAGGTGTTTCTGGCTGATGC
ATTCGAAACGGGTGATGCCGGTTATATTGCCAAGGCTTTGGGTCTTGTCGCTCGCGCGAAAGGCATGACCAAAATTGCGC
GGCAAACGGGTTTGGCGCGTGAGCAACTCTATCGTTCGTTAAGTGAAAACGGAAACCCGACGCTTGAAACAACAATAGCG
GTTATGAAGGCAGTGGGATTTCAGATCACCGGAAAACGCGCTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References