185512

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4675968..4676331 Replicon chromosome
Accession NZ_CP066970
Organism Xanthomonas campestris pv. campestris strain 11085

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH300_RS20380 Protein ID WP_011270059.1
Coordinates 4675968..4676102 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH300_RS20385 Protein ID WP_011038999.1
Coordinates 4676179..4676331 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH300_RS20360 (JH300_20330) 4671232..4672884 - 1653 WP_057673525.1 M28 family metallopeptidase -
JH300_RS20365 (JH300_20335) 4673049..4673993 - 945 WP_057673527.1 MBL fold metallo-hydrolase -
JH300_RS20370 (JH300_20340) 4674077..4675366 - 1290 WP_057673596.1 tryptophan--tRNA ligase -
JH300_RS20375 (JH300_20345) 4675526..4675735 - 210 WP_011038998.1 CsbD family protein -
JH300_RS20380 (JH300_20350) 4675968..4676102 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH300_RS20385 (JH300_20355) 4676179..4676331 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH300_RS20390 (JH300_20360) 4676442..4677365 - 924 WP_057673597.1 arginase -
JH300_RS20395 (JH300_20365) 4677679..4678140 + 462 WP_057673529.1 roadblock/LC7 domain-containing protein -
JH300_RS20400 (JH300_20370) 4678223..4678582 + 360 WP_011039002.1 hypothetical protein -
JH300_RS20405 (JH300_20375) 4678685..4679602 + 918 WP_057673531.1 hypothetical protein -
JH300_RS20410 (JH300_20380) 4679599..4680141 + 543 WP_057673534.1 GTPase -
JH300_RS20415 (JH300_20385) 4680477..4681160 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185512 WP_011270059.1 NZ_CP066970:c4676102-4675968 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185512 NZ_CP088273:c2596752-2596384 [Phyllobacterium sp. T1293]
ATGATCCTCGCCGACACTTCAGTATGGATAGATCATCTGCGTTATGGCGATGCGGAGCTAGTACGACATCTCGAAGCTGC
GCAAATATTAATCCATCCGTTTATCGTGGGGGAACTGGCTCTGGGAAATTTGCGGCAGCGTGAACTCATTTTGAACAGCC
TTCAGGATTTGCCGAAAGTGCAGGTGGCCGATGACAAAGAGATCTCATATTTCATTGACGCTGAAACAATCTTTGATCTT
GGTCTCGGCTATGTCGATGCGCACTTGCTGGCTGCAACACGGCTGACGCCCGGCACGCGGTTATGGACAAGAGACAAAAG
ATTGGCCGCGGCCGCAACTCGTCTACGGCTCCAAGCGGATTTTCACTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185512 WP_011038999.1 NZ_CP066970:c4676331-4676179 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185512 NZ_CP088273:c2596955-2596749 [Phyllobacterium sp. T1293]
ATGCGTACCACGCTTGCTCTCGATGATGATTTGGTTGCCAAAGCGCAGGAATATACGGGCTTGCGGGAGAAATCCGCGCT
TATGCGTGCGGCCCTCAAGGCGTTGATCAACATTGAGAGCGCCCGTAGATTGGCACTTCTGGGTGGGAGTGAACCTGATT
TGAACACTATACCCCGGCGTCAGATTACGCCGGACGTCCAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References