185509

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 431372..431735 Replicon chromosome
Accession NZ_CP066969
Organism Xanthomonas campestris strain 10-16

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH307_RS01780 Protein ID WP_011270059.1
Coordinates 431601..431735 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH307_RS01775 Protein ID WP_011038999.1
Coordinates 431372..431524 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH307_RS01745 (JH307_01735) 426544..427227 - 684 WP_274502292.1 dTMP kinase -
JH307_RS01750 (JH307_01740) 427562..428104 - 543 WP_274509389.1 GTPase -
JH307_RS01755 (JH307_01745) 428101..429018 - 918 WP_274348093.1 hypothetical protein -
JH307_RS01760 (JH307_01750) 429121..429480 - 360 WP_011039002.1 hypothetical protein -
JH307_RS01765 (JH307_01755) 429563..430024 - 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH307_RS01770 (JH307_01760) 430338..431261 + 924 WP_070694619.1 arginase -
JH307_RS01775 (JH307_01765) 431372..431524 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH307_RS01780 (JH307_01770) 431601..431735 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH307_RS01785 (JH307_01775) 431966..432175 + 210 WP_011038998.1 CsbD family protein -
JH307_RS01790 (JH307_01780) 432335..433624 + 1290 WP_043922084.1 tryptophan--tRNA ligase -
JH307_RS01795 (JH307_01785) 433708..434652 + 945 WP_274509390.1 MBL fold metallo-hydrolase -
JH307_RS01800 (JH307_01790) 434817..436469 + 1653 WP_274509799.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185509 WP_011270059.1 NZ_CP066969:431601-431735 [Xanthomonas campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185509 NZ_CP088273:2038788-2039186 [Phyllobacterium sp. T1293]
ATGACGCATACCCACATGCTCGACACCAATATGATTTCAGGTTTGATACGCCACCAAAACAGCCATTTAACGGAGAAGGT
CAGGCAGCATAGCAAAACGGTCTGCACGAGCATTATCGTGGCAGCAGAACTTCGCTATGGGGTAGACAAGAAGGGCTCCG
TACATTTGCGCGCGCGCATTGAAGAATTGCTGTCGATTATCGACGTTTTGCCGTTTGAAGGCCCTGCGGACATGCATTAT
GCCCGCATCCGCAATGAGCTTGAGGCGGCAGGAAAGACGATCGGCCCCAATGATCTTCTGATTGCAGCTCACGCCTGCGC
GACCGGCACGGTACTGGTGACCGACAATATGAAAGAGTTCAACCGCGTCCCCGGTCTCCAAATCGAAAACTGGCTATAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185509 WP_011038999.1 NZ_CP066969:431372-431524 [Xanthomonas campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185509 NZ_CP088273:2038555-2038791 [Phyllobacterium sp. T1293]
ATGCAGGAACGACAGGTAAAATTATTTCGCAATGGCAGGAATCAGGCGGTGAGAATCCCGGTGGAATTTGAAATGCCGGG
CGATACCGCAATCATGCACCGTGAGGGCAACCGGCTGATTATCGAGCCTGTGAAACAACGGTCCTTGATTGAATTTCTGG
CAAATCTCGAACCACTCGCTGACGAGTTTCCTGATGTCGACGAAGGGCTGCTCCCACTGCGTGAGATCGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References