185507

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 365853..366216 Replicon chromosome
Accession NZ_CP066968
Organism Xanthomonas campestris pv. incanae strain 16-8

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH274_RS01550 Protein ID WP_011270059.1
Coordinates 366082..366216 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH274_RS01545 Protein ID WP_011038999.1
Coordinates 365853..366005 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH274_RS01515 (JH274_01515) 361031..361708 - 678 WP_076035807.1 dTMP kinase -
JH274_RS01520 (JH274_01520) 362043..362585 - 543 WP_076035808.1 GTPase -
JH274_RS01525 (JH274_01525) 362582..363499 - 918 WP_223647313.1 hypothetical protein -
JH274_RS01530 (JH274_01530) 363602..363961 - 360 WP_011039002.1 hypothetical protein -
JH274_RS01535 (JH274_01535) 364044..364505 - 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH274_RS01540 (JH274_01540) 364819..365742 + 924 WP_057673597.1 arginase -
JH274_RS01545 (JH274_01545) 365853..366005 + 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH274_RS01550 (JH274_01550) 366082..366216 + 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH274_RS01555 (JH274_01555) 366447..366656 + 210 WP_011038998.1 CsbD family protein -
JH274_RS01560 (JH274_01560) 366816..368105 + 1290 WP_043922084.1 tryptophan--tRNA ligase -
JH274_RS01565 (JH274_01565) 368188..369132 + 945 WP_181921549.1 MBL fold metallo-hydrolase -
JH274_RS01570 (JH274_01570) 369297..370949 + 1653 WP_181921563.1 M28 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185507 WP_011270059.1 NZ_CP066968:366082-366216 [Xanthomonas campestris pv. incanae]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185507 NZ_CP088273:c1709281-1708976 [Phyllobacterium sp. T1293]
ATGAGATTGATTGAGAAGACGGACACTTTTTTAAGCTGGATTGATGGCTTGAGAGACCAAAGAGCCAGAGCCAGAATTGC
GATGCGACTTGATCGCTTGATCGACGGCAATCTCGGCGACATCAAACTTGTCGGCGACGGCGTCAGTGAACTTCGAATTG
ATTATGGTCCCGGTTACCGCGTCTATTTCATCGAGCGAAACGACGTCCTGATTATCCTGTTGTGTGGTGGAGACAAGAGC
ACTCAGGATCGCGATATCAGAAAGGCAAAGACAATGGCTGCTGCTTTAAGGAAAGTAAGATCATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185507 WP_011038999.1 NZ_CP066968:365853-366005 [Xanthomonas campestris pv. incanae]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185507 NZ_CP088273:c1708979-1708674 [Phyllobacterium sp. T1293]
ATGATAAAGTTGAGCCCATACGATACTGCCCAGCACCTCGATTCCGAAGAAATGATCGAAGAGTATCTGTTGGCAACGTG
CGAAGATGGTACTCCGTCGGAAATAGCCCGCGCTTTGGGTAACATTGCGCGCGCACGCGGTATCACCGAGCTTGCCCAAA
AAACCGGCCTTACCCGTCAAGCGCTATACAAAGCTTTGAGCGGTGAAGGTAATCCTGGATTGGCAACGATTACTAAGGTG
GCTGACGTATTGGGACTCAAGCTGTCTTTGGTGCCTGTGGCGACCAAAAAGCAGGATGCTGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References