Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 20937..21342 Replicon chromosome
Accession NZ_CP066968
Organism Xanthomonas campestris pv. incanae strain 16-8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH274_RS00105 Protein ID WP_274395881.1
Coordinates 20937..21092 (-) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH274_RS00110 Protein ID WP_220353927.1
Coordinates 21094..21342 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH274_RS00085 (JH274_00085) 18378..18652 + 275 Protein_16 integrase core domain-containing protein -
JH274_RS00090 (JH274_00090) 18661..19104 + 444 WP_044474917.1 hypothetical protein -
JH274_RS00095 (JH274_00095) 19305..19790 - 486 Protein_18 IS3-like element IS1404 family transposase -
JH274_RS00100 (JH274_00100) 20021..20881 + 861 WP_274395880.1 DUF2971 domain-containing protein -
JH274_RS00105 (JH274_00105) 20937..21092 - 156 WP_274395881.1 hypothetical protein Toxin
JH274_RS00110 (JH274_00110) 21094..21342 - 249 WP_220353927.1 Arc family DNA-binding protein Antitoxin
JH274_RS00115 (JH274_00115) 21480..22595 - 1116 WP_012439694.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH274_RS00120 (JH274_00120) 22582..22788 - 207 WP_014509615.1 hypothetical protein -
JH274_RS00125 (JH274_00125) 23048..23563 + 516 WP_116891512.1 hypothetical protein -
JH274_RS00130 (JH274_00130) 23595..24860 - 1266 WP_043877851.1 phospholipase D-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 19305..19781 476


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5665.63 Da        Isoelectric Point: 4.3220

>T185506 WP_274395881.1 NZ_CP066968:c21092-20937 [Xanthomonas campestris pv. incanae]
VILLDTNVIFGPNLHVVAWIDAQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185506 NZ_CP088273:c1708979-1708674 [Phyllobacterium sp. T1293]
ATGATAAAGTTGAGCCCATACGATACTGCCCAGCACCTCGATTCCGAAGAAATGATCGAAGAGTATCTGTTGGCAACGTG
CGAAGATGGTACTCCGTCGGAAATAGCCCGCGCTTTGGGTAACATTGCGCGCGCACGCGGTATCACCGAGCTTGCCCAAA
AAACCGGCCTTACCCGTCAAGCGCTATACAAAGCTTTGAGCGGTGAAGGTAATCCTGGATTGGCAACGATTACTAAGGTG
GCTGACGTATTGGGACTCAAGCTGTCTTTGGTGCCTGTGGCGACCAAAAAGCAGGATGCTGCTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8917.18 Da        Isoelectric Point: 12.0013

>AT185506 WP_220353927.1 NZ_CP066968:c21342-21094 [Xanthomonas campestris pv. incanae]
MPSFTVRNIPEDVHRAIRARAAQHGRSTEAEIRAILESAARPADRVKLGALLVDIGRDAGLTAKRLTPSPSYATRPRSSR
SV

Download         Length: 249 bp

>AT185506 NZ_CP088273:c1709281-1708976 [Phyllobacterium sp. T1293]
ATGAGATTGATTGAGAAGACGGACACTTTTTTAAGCTGGATTGATGGCTTGAGAGACCAAAGAGCCAGAGCCAGAATTGC
GATGCGACTTGATCGCTTGATCGACGGCAATCTCGGCGACATCAAACTTGTCGGCGACGGCGTCAGTGAACTTCGAATTG
ATTATGGTCCCGGTTACCGCGTCTATTTCATCGAGCGAAACGACGTCCTGATTATCCTGTTGTGTGGTGGAGACAAGAGC
ACTCAGGATCGCGATATCAGAAAGGCAAAGACAATGGCTGCTGCTTTAAGGAAAGTAAGATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References