185505

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4602867..4603230 Replicon chromosome
Accession NZ_CP066966
Organism Xanthomonas campestris pv. campestris strain 08305

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH275_RS20105 Protein ID WP_011270059.1
Coordinates 4602867..4603001 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH275_RS20110 Protein ID WP_011038999.1
Coordinates 4603078..4603230 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH275_RS20085 (JH275_20015) 4598131..4599783 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH275_RS20090 (JH275_20020) 4599948..4600892 - 945 WP_274495651.1 MBL fold metallo-hydrolase -
JH275_RS20095 (JH275_20025) 4600976..4602265 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH275_RS20100 (JH275_20030) 4602425..4602634 - 210 WP_011038998.1 CsbD family protein -
JH275_RS20105 (JH275_20035) 4602867..4603001 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH275_RS20110 (JH275_20040) 4603078..4603230 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH275_RS20115 (JH275_20045) 4603341..4604264 - 924 WP_011039000.1 arginase -
JH275_RS20120 (JH275_20050) 4604578..4605039 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH275_RS20125 (JH275_20055) 4605122..4605481 + 360 WP_011039002.1 hypothetical protein -
JH275_RS20130 (JH275_20060) 4605584..4606501 + 918 WP_011039003.1 hypothetical protein -
JH275_RS20135 (JH275_20065) 4606498..4607040 + 543 WP_011039004.1 GTPase -
JH275_RS20140 (JH275_20070) 4607375..4608058 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185505 WP_011270059.1 NZ_CP066966:c4603001-4602867 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185505 NZ_CP088273:468123-468269 [Phyllobacterium sp. T1293]
GTGAGTGAAAGAGAGGGTTCGCGCATTGGTGTATTTTTGTTCGGTGAAGTCAGGGTGTTTCATCGCCCGCACCCATCGCC
GGATACCGATAAAGGCGCGGTTGCCGCTATCCGAAAATGGCTTGAGAGCCATGGAGTAAGACCTTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185505 WP_011038999.1 NZ_CP066966:c4603230-4603078 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185505 NZ_CP088273:468266-468604 [Phyllobacterium sp. T1293]
TTGAAGAACATTCTTGATGTGGATGGCCACAAGGCTGTCATTTCATTTGATCCTGAACTGGGCCTGATAAGAGGTGAGTT
TCTCGGACTGAATGGCGGTGCGGATTTTTACGCGCAAAGCGTCGAGGGGCTTCTTTTGGAAGGGAGAAAGTCTCTTCAGG
TCTTTCTTGAGATGTGCGCGGAGAAGGGCATCGCGCCATTTCGCGAATTTTCCGGCCGTTTTAATGTTCGTCTGACTGCT
GACGTTCACGAGGCTGCCGTTTTGGCAGCCGCAGCAGAGAACAAAAGTCTGAATGAATGGATTGCCGGGGCAATCGAAGC
GGCAACACGGGCCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References