Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4591618..4591981 Replicon chromosome
Accession NZ_CP066956
Organism Xanthomonas campestris pv. incanae strain 8-14

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH279_RS20080 Protein ID WP_011270059.1
Coordinates 4591618..4591752 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH279_RS20085 Protein ID WP_011038999.1
Coordinates 4591829..4591981 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH279_RS20060 (JH279_19975) 4586885..4588537 - 1653 WP_274391853.1 M28 family metallopeptidase -
JH279_RS20065 (JH279_19980) 4588702..4589646 - 945 WP_181921549.1 MBL fold metallo-hydrolase -
JH279_RS20070 (JH279_19985) 4589729..4591018 - 1290 WP_043922084.1 tryptophan--tRNA ligase -
JH279_RS20075 (JH279_19990) 4591178..4591387 - 210 WP_011038998.1 CsbD family protein -
JH279_RS20080 (JH279_19995) 4591618..4591752 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH279_RS20085 (JH279_20000) 4591829..4591981 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH279_RS20090 (JH279_20005) 4592092..4593015 - 924 WP_057673597.1 arginase -
JH279_RS20095 (JH279_20010) 4593329..4593790 + 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH279_RS20100 (JH279_20015) 4593873..4594232 + 360 WP_011039002.1 hypothetical protein -
JH279_RS20105 (JH279_20020) 4594335..4595252 + 918 WP_223647313.1 hypothetical protein -
JH279_RS20110 (JH279_20025) 4595249..4595791 + 543 WP_076035808.1 GTPase -
JH279_RS20115 (JH279_20030) 4596126..4596803 + 678 WP_076035807.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185495 WP_011270059.1 NZ_CP066956:c4591752-4591618 [Xanthomonas campestris pv. incanae]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185495 NZ_CP088269:4101131-4101349 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185495 WP_011038999.1 NZ_CP066956:c4591981-4591829 [Xanthomonas campestris pv. incanae]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185495 NZ_CP088269:4100730-4101104 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References