Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 5032864..5033270 Replicon chromosome
Accession NZ_CP066955
Organism Xanthomonas campestris pv. campestris strain 08288

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JH309_RS21865 Protein ID WP_267129426.1
Coordinates 5033115..5033270 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JH309_RS21860 Protein ID WP_070694028.1
Coordinates 5032864..5033118 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH309_RS21835 (JH309_21775) 5028365..5029204 + 840 WP_014509612.1 SDR family oxidoreductase -
JH309_RS21840 (JH309_21780) 5029348..5030613 + 1266 WP_040942139.1 phospholipase D-like domain-containing protein -
JH309_RS21845 (JH309_21785) 5030645..5031160 - 516 WP_070694020.1 hypothetical protein -
JH309_RS21850 (JH309_21790) 5031417..5031623 + 207 WP_070694021.1 hypothetical protein -
JH309_RS21855 (JH309_21795) 5031610..5032725 + 1116 WP_070694026.1 type II toxin-antitoxin system RelE/ParE family toxin -
JH309_RS21860 (JH309_21800) 5032864..5033118 + 255 WP_070694028.1 Arc family DNA-binding protein Antitoxin
JH309_RS21865 (JH309_21805) 5033115..5033270 + 156 WP_267129426.1 hypothetical protein Toxin
JH309_RS21870 (JH309_21810) 5033325..5034296 - 972 WP_081390822.1 DUF2971 domain-containing protein -
JH309_RS21875 (JH309_21815) 5034455..5036074 + 1620 WP_139328770.1 alpha/beta hydrolase-fold protein -
JH309_RS21880 (JH309_21820) 5036345..5036746 - 402 WP_162277263.1 DUF2384 domain-containing protein -
JH309_RS21885 (JH309_21825) 5036978..5037409 + 432 WP_206419606.1 hypothetical protein -
JH309_RS21890 (JH309_21830) 5037438..5037794 - 357 WP_162277264.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5032864..5043989 11125


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Arc-like DNA binding domain

(1-39)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5681.63 Da        Isoelectric Point: 4.3220

>T185493 WP_267129426.1 NZ_CP066955:5033115-5033270 [Xanthomonas campestris pv. campestris]
VTLLDTNVIFGPNLHVVAWIDVQAVETLFLSVVTVAELRSGDIQDFRPLMK

Download         Length: 156 bp

>T185493 NZ_CP088269:2004106-2004208 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9028.44 Da        Isoelectric Point: 10.3861

>AT185493 WP_070694028.1 NZ_CP066955:5032864-5033118 [Xanthomonas campestris pv. campestris]
MPSFTVRNIPEDVHRAIWARAAQHGRSTEAEIRAILESAAKPADQVKLGALLVDIGRDAGLTAKEADAFAKLRDKAAIKP
IGLK

Download         Length: 255 bp

>AT185493 NZ_CP088269:c2004215-2004070 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References