185492

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4701514..4701877 Replicon chromosome
Accession NZ_CP066955
Organism Xanthomonas campestris pv. campestris strain 08288

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH309_RS20510 Protein ID WP_011270059.1
Coordinates 4701514..4701648 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH309_RS20515 Protein ID WP_011038999.1
Coordinates 4701725..4701877 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH309_RS20490 (JH309_20430) 4696778..4698430 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH309_RS20495 (JH309_20435) 4698595..4699539 - 945 WP_068574725.1 MBL fold metallo-hydrolase -
JH309_RS20500 (JH309_20440) 4699623..4700912 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH309_RS20505 (JH309_20445) 4701072..4701281 - 210 WP_011038998.1 CsbD family protein -
JH309_RS20510 (JH309_20450) 4701514..4701648 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH309_RS20515 (JH309_20455) 4701725..4701877 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH309_RS20520 (JH309_20460) 4701988..4702911 - 924 WP_011039000.1 arginase -
JH309_RS20525 (JH309_20465) 4703225..4703686 + 462 WP_042595651.1 roadblock/LC7 domain-containing protein -
JH309_RS20530 (JH309_20470) 4703769..4704128 + 360 WP_011039002.1 hypothetical protein -
JH309_RS20535 (JH309_20475) 4704231..4705148 + 918 WP_057673531.1 hypothetical protein -
JH309_RS20540 (JH309_20480) 4705145..4705687 + 543 WP_057673534.1 GTPase -
JH309_RS20545 (JH309_20485) 4706023..4706706 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185492 WP_011270059.1 NZ_CP066955:c4701648-4701514 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185492 NZ_CP088269:848180-848590 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185492 WP_011038999.1 NZ_CP066955:c4701877-4701725 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185492 NZ_CP088269:847933-848199 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References