185490

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4658924..4659287 Replicon chromosome
Accession NZ_CP066953
Organism Xanthomonas campestris pv. campestris strain 10103

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH282_RS20420 Protein ID WP_011270059.1
Coordinates 4658924..4659058 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH282_RS20425 Protein ID WP_011038999.1
Coordinates 4659135..4659287 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH282_RS20400 (JH282_20395) 4654188..4655840 - 1653 WP_043877841.1 M28 family metallopeptidase -
JH282_RS20405 (JH282_20400) 4656005..4656949 - 945 WP_068574725.1 MBL fold metallo-hydrolase -
JH282_RS20410 (JH282_20405) 4657033..4658322 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JH282_RS20415 (JH282_20410) 4658482..4658691 - 210 WP_011038998.1 CsbD family protein -
JH282_RS20420 (JH282_20415) 4658924..4659058 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH282_RS20425 (JH282_20420) 4659135..4659287 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH282_RS20430 (JH282_20425) 4659398..4660321 - 924 WP_011039000.1 arginase -
JH282_RS20435 (JH282_20430) 4660635..4661096 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JH282_RS20440 (JH282_20435) 4661179..4661538 + 360 WP_011039002.1 hypothetical protein -
JH282_RS20445 (JH282_20440) 4661641..4662558 + 918 WP_011039003.1 hypothetical protein -
JH282_RS20450 (JH282_20445) 4662555..4663097 + 543 WP_011039004.1 GTPase -
JH282_RS20455 (JH282_20450) 4663432..4664115 + 684 WP_050911792.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185490 WP_011270059.1 NZ_CP066953:c4659058-4658924 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185490 NZ_CP088269:331004-331372 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCTGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185490 WP_011038999.1 NZ_CP066953:c4659287-4659135 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185490 NZ_CP088269:330786-331007 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References