185488

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4707452..4707815 Replicon chromosome
Accession NZ_CP066949
Organism Xanthomonas campestris pv. campestris strain 0659

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH278_RS20730 Protein ID WP_011270059.1
Coordinates 4707452..4707586 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH278_RS20735 Protein ID WP_011038999.1
Coordinates 4707663..4707815 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH278_RS20710 (JH278_20690) 4702717..4704369 - 1653 WP_227972034.1 M28 family metallopeptidase -
JH278_RS20715 (JH278_20695) 4704533..4705477 - 945 WP_274375307.1 MBL fold metallo-hydrolase -
JH278_RS20720 (JH278_20700) 4705561..4706850 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH278_RS20725 (JH278_20705) 4707010..4707219 - 210 WP_011038998.1 CsbD family protein -
JH278_RS20730 (JH278_20710) 4707452..4707586 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH278_RS20735 (JH278_20715) 4707663..4707815 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH278_RS20740 (JH278_20720) 4707926..4708849 - 924 WP_012439504.1 arginase -
JH278_RS20745 (JH278_20725) 4709163..4709624 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH278_RS20750 (JH278_20730) 4709707..4710066 + 360 WP_011039002.1 hypothetical protein -
JH278_RS20755 (JH278_20735) 4710169..4711086 + 918 WP_012439506.1 hypothetical protein -
JH278_RS20760 (JH278_20740) 4711083..4711625 + 543 WP_012439507.1 GTPase -
JH278_RS20765 (JH278_20745) 4711960..4712643 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185488 WP_011270059.1 NZ_CP066949:c4707586-4707452 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185488 NZ_CP088265:c3698691-3697372 [Leclercia sp. G3L]
ATGCGCGCAAAACGTCTGACTGTCGCGATGAATGGCGATGTGATAGGCACGCTGCATCGTGATGGCAGCGGGGCGATGTC
CTTTCAGTATGCCCCAGCGTGGCTGGCAGAGCCGGGTTCGCGAGCGATCTCGCTCTCTCTGCCGCTGCAACACGGCAGGA
TTAGCGGCGCGCCGGTCTTCAATTTCTTCAGCAATCTGCTGCCTGACTCCGAGGCGATTATTGCCCGCATGCAGGCCCGT
TTTCAAGTGGAAACCACGCATCCTTTCGATCTGCTCGCCAGCGTTGGGCGTGACTGCGTCGGCGCCATTCAGCTCTATCC
GCCGGGGCAGGAGATCCCCCCGGTAACGGATATCGTGGCCGAACCGCTGGATGACGATCAGATTGCCGCGCTGCTCGAGG
GCTACCAGATGGCGCCGCTGGGGATGACAGAGGAGGGCGCCGATTTTCGCATTTCGCTGGCCGGGGCGCAGGAGAAAACG
GCGCTGCTGTGGTATCAGGATCGCTGGCAACGGCCCCAGGGCAGCACCCCAACCAGCCATATCTTCAAGCTGCCGATAGG
TAGAATAGAGCAGAATAACATTGACCTGAGCGAAAGCTGCGAAAACGAATGGCTCTGTTTGCGTATCGCCAAAGCCTTTG
GTTTCCCGGTCGCGCATGCCGACATGGCACAGTTTGGCCGGAAAAAGGTGCTGATTATCGAGCGTTTCGATCGTCGATGG
GCCCGCAGCGGCTGGCTGATGCGCTTGCCGCAGGAGGACTTTTGCCAGGCGCTGGGCGTGTCGCCAGCGCTGAAATATGA
GTCTCACGGTGGCCCCGGGATTGCAGACGCCATGAAGCTGCTGCTTGGTTCTCGCCTGGCGGGGCAGGATCGCGAGATGT
TCTTTAAGGCGCAGATCCTTTTCTGGATGCTGGCCGCCATCGATGGCCACGGTAAAAATTTTAGCCTGTTTATTGAGGCC
GACTCCTCGTTTCGCATGGCCCCGCTGTATGACGTGATTTCCGCGTTTCCGCTGTTCGACGCCGGGGGGATCCCGGTCAA
AAAGGCGAAGATGGCGATGGCGCTACAGGGAAAAAACCGGCAGTACCATTTCGCGATGATCCAGCCGCGACACTTTATCA
GCACCGCCGCCTTTGCGGGATTTTCGCAGGAGGCTGCCCGCCGTTTGATGACGGAGATGGCCGCGGTTACCGACGACGTT
ATCGCCACCGTCAGGGCAGAACTGCCGACGGATTTTCCGCTGCCGGTGAGCGAGGCTATTTTTCGCGGTTTAGCCCGCCA
GGCGGCGCGGATAGGGCGATTCAATGAGTTAACCCCGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185488 WP_011038999.1 NZ_CP066949:c4707815-4707663 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185488 NZ_CP088265:c3698946-3698695 [Leclercia sp. G3L]
ATGAAGGTGACATCGGCAGACGCACTGGCGCAGGCCGTCCGGGATCAGCGTAAGGTCAATAAGTTAACCCAAACGGCGAC
GGCTGAACAGGTAGGTATTAAACAAACCACCGTATCGGATTTCGAGAACAAACCGGGCTCTACCAAGCTGGACACCTTGT
TCAAAATCCTTGCGGCGCTGGACCTGGAACTGCACGTGGTAAAACGCGGTGCCACGCTGCCGGACAATAACGCCTGGACG
AAGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References