185486

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4708800..4709163 Replicon chromosome
Accession NZ_CP066948
Organism Xanthomonas campestris pv. campestris strain 0793

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH266_RS20740 Protein ID WP_011270059.1
Coordinates 4708800..4708934 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH266_RS20745 Protein ID WP_011038999.1
Coordinates 4709011..4709163 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH266_RS20720 (JH266_20675) 4704065..4705717 - 1653 WP_227972034.1 M28 family metallopeptidase -
JH266_RS20725 (JH266_20680) 4705881..4706825 - 945 WP_274375307.1 MBL fold metallo-hydrolase -
JH266_RS20730 (JH266_20685) 4706909..4708198 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH266_RS20735 (JH266_20690) 4708358..4708567 - 210 WP_011038998.1 CsbD family protein -
JH266_RS20740 (JH266_20695) 4708800..4708934 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH266_RS20745 (JH266_20700) 4709011..4709163 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH266_RS20750 (JH266_20705) 4709274..4710197 - 924 WP_012439504.1 arginase -
JH266_RS20755 (JH266_20710) 4710511..4710972 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH266_RS20760 (JH266_20715) 4711055..4711414 + 360 WP_011039002.1 hypothetical protein -
JH266_RS20765 (JH266_20720) 4711517..4712434 + 918 WP_012439506.1 hypothetical protein -
JH266_RS20770 (JH266_20725) 4712431..4712973 + 543 WP_012439507.1 GTPase -
JH266_RS20775 (JH266_20730) 4713308..4713991 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185486 WP_011270059.1 NZ_CP066948:c4708934-4708800 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185486 NZ_CP088265:3114800-3114902 [Leclercia sp. G3L]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185486 WP_011038999.1 NZ_CP066948:c4709163-4709011 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185486 NZ_CP088265:c3114941-3114734 [Leclercia sp. G3L]
AAAGTCCGCAACAGGAAAATGCGTTTACTTTCAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAA
ATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCACTTTAAGAATAGATGAC
GACGCCAGGTTTTCCAGTCCGCAGCAAAAGTGGCCTGAAAAAAAGCGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References