185484

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4708793..4709156 Replicon chromosome
Accession NZ_CP066947
Organism Xanthomonas campestris pv. campestris strain 0792

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JH257_RS20740 Protein ID WP_011270059.1
Coordinates 4708793..4708927 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JH257_RS20745 Protein ID WP_011038999.1
Coordinates 4709004..4709156 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JH257_RS20720 (JH257_20675) 4704058..4705710 - 1653 WP_227972034.1 M28 family metallopeptidase -
JH257_RS20725 (JH257_20680) 4705874..4706818 - 945 WP_274375307.1 MBL fold metallo-hydrolase -
JH257_RS20730 (JH257_20685) 4706902..4708191 - 1290 WP_029217012.1 tryptophan--tRNA ligase -
JH257_RS20735 (JH257_20690) 4708351..4708560 - 210 WP_011038998.1 CsbD family protein -
JH257_RS20740 (JH257_20695) 4708793..4708927 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JH257_RS20745 (JH257_20700) 4709004..4709156 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JH257_RS20750 (JH257_20705) 4709267..4710190 - 924 WP_012439504.1 arginase -
JH257_RS20755 (JH257_20710) 4710504..4710965 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
JH257_RS20760 (JH257_20715) 4711048..4711407 + 360 WP_011039002.1 hypothetical protein -
JH257_RS20765 (JH257_20720) 4711510..4712427 + 918 WP_012439506.1 hypothetical protein -
JH257_RS20770 (JH257_20725) 4712424..4712966 + 543 WP_012439507.1 GTPase -
JH257_RS20775 (JH257_20730) 4713301..4713984 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T185484 WP_011270059.1 NZ_CP066947:c4708927-4708793 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T185484 NZ_CP088265:c2272226-2271903 [Leclercia sp. G3L]
ATGACCACACCACTTACGTTAAGGAGCATCTCTGACTTTCGCGATACCTGGCTTGAGGACTTTTTTCTATATGGACGTCC
ACATGGAAAAATCCCGGCAGAGATAGCGTCAGCTCTGATGCGAAAACTCGACATCATCAACGCAGCGACCTCGTATCGGG
ATCTGCGTAGCCCACCCGGCAACAAGCTTGAAGCGTTGAGCTCGCCGCTTCTGGGTTGTTATTCGATACGCGTGAACAGG
CAATACCGACTGATTTTCATCTGGTCAGGCGGTAAGGCGAAAGGGATTTATCTTGATCCTCATACCTACAATGCTCACCG
ATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT185484 WP_011038999.1 NZ_CP066947:c4709156-4709004 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT185484 NZ_CP088265:c2271859-2271515 [Leclercia sp. G3L]
ATGGCATTCACAAACAGCACCCGTAAACCGACCACACCCGGCGATATTCTGCTTCACGAGTTTCTTGAGCCGCTGCATTT
AAAAATTGCCGATCTGGCCGAGATGCTTAACGTGCACAGAAACAGCGTCAGCGCGCTGGTCAATAACAACCGAAAACTGA
CCACGGACATGGCCGTACGGCTAGCCCGGGCTTTTGATACCACCATTGAGTTTTGGCTGAACTTGCAGCTGAACGTGGAT
ATCTGGGAAATTCAGCACGACGAGCGCATGCAGGCAGAACATCAGCAGATCATTACTGCGGCGGAGATGGTTGAGAGGAA
GAAAGCGCAGCAGTCTGTAGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References